| Identification | More | [Name]
N-Cbz-L-Leucine | [CAS]
2018-66-8 | [Synonyms]
BENZYLOXYCARBONYL-L-LEUCINE
CBZ-LEUCINE
CBZ-LEU-OH
CBZ-L-LEUCINE
CBZ-L-LEU-OH
N-ALPHA-BENZYLOXYCARBONYL-L-LEUCINE
N-ALPHA-CARBOBENZOXY-L-LEUCINE
N-ALPHA-CBZ-L-LEUCINE
N-BENZYLOXYCARBONYL-L-LEUCINE
N-CARBOBENZOXY-L-LEUCINE
N-CARBOBENZYLOXY-L-LEUCINE
N-CBZ-L-LEUCINE
N-CBZ-L-LEUCINE-OH
Z-LEUCINE
Z-LEU-OH
Z-L-LEUCINE
Z-L-LEU-OH
benzyloxycarbonylleucine
carbobenzoxyleucine
carbobenzoxy-l-leucine | [EINECS(EC#)]
217-960-3 | [Molecular Formula]
C14H19NO4 | [MDL Number]
MFCD00026494 | [Molecular Weight]
265.3 | [MOL File]
2018-66-8.mol |
| Chemical Properties | Back Directory | [Appearance]
yellow oil or weak solid | [alpha ]
-17 º (c=2, ethanol) | [Boiling point ]
408.52°C (rough estimate) | [density ]
1 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.512(lit.)
| [Fp ]
85 °F
| [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
viscous liquid
| [pka]
4.00±0.21(Predicted) | [color ]
Colorless to Light yellow | [Specific Gravity]
1.0 | [optical activity]
[α]20/D 17°, c = 2 in ethanol | [Water Solubility ]
Not miscible or difficult to mix in water. Soluble in chloroform, DMSO and methanol. | [BRN ]
1253861 | [CAS DataBase Reference]
2018-66-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R10:Flammable.
R20/22:Harmful by inhalation and if swallowed .
R37/38:Irritating to respiratory system and skin .
R40:Limited evidence of a carcinogenic effect.
R41:Risk of serious damage to eyes.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 1993 3/PG 3
| [WGK Germany ]
3
| [RTECS ]
OH2921000
| [HS Code ]
29242990 |
| Hazard Information | Back Directory | [Chemical Properties]
yellow oil or weak solid | [Uses]
Reactant for:
- Peptide-based preparation of potential antitumor agents
- Preparation of cyclopropyl peptidomimetics
- Peptide synthesis
| [Definition]
ChEBI: A L-leucine derivative obtained by the substitution of a benzyloxycarbonyl group on the nitrogen atom. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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