| Identification | More | [Name]
tert-Butyl carbazate | [CAS]
870-46-2 | [Synonyms]
AKOS B028820
BOC-HYDRAZIDE
BOC-HYDRAZINE
BOC-NHNH2
+-BUTYL CARBAZATE
CARBAZIC ACID TERT-BUTYL ESTER
CARBAZINIC ACID TERT-BUTYL ESTER
CARBONIC ACID TERT-BUTYL ESTER HYDRAZIDE
HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER
LABOTEST-BB LT00053500
N-T-BUTOXYCARBONYL-HYDRAZIDE
T-BOC-HYDRAZIDE
T-BUTOXYCARBONYL HYDRAZIDE
T-BUTYLCARBAZATE
T-BUTYLOXYCARBONYL-HYDRAZIDE
TERT-BOC-HYDRAZIDE
TERT-BUTOXYCARBONYL HYDRAZIDE
TERT-BUTOXYCARBONYLHYDRAZINE
TERT-BUTYLOXYCARBAZATE
tert-butyloxycarbonyl-hydrazide | [EINECS(EC#)]
212-795-3 | [Molecular Formula]
C5H12N2O2 | [MDL Number]
MFCD00007593 | [Molecular Weight]
132.16 | [MOL File]
870-46-2.mol |
| Chemical Properties | Back Directory | [Appearance]
White to pale yellow lumps | [Melting point ]
39-42 °C (lit.) | [Boiling point ]
63-65 °C/0.1 mmHg (lit.) | [density ]
1.02
| [refractive index ]
1.4496 (estimate) | [Fp ]
197 °F
| [storage temp. ]
Store at RT. | [solubility ]
Soluble in ethanol and methanol. | [form ]
Crystalline Lumps | [pka]
10.74±0.20(Predicted) | [color ]
White to slightly yellow | [Sensitive ]
Moisture Sensitive | [BRN ]
1756967 | [InChIKey]
DKACXUFSLUYRFU-UHFFFAOYSA-N | [CAS DataBase Reference]
870-46-2(CAS DataBase Reference) | [EPA Substance Registry System]
870-46-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T-F,T,F | [Risk Statements ]
R48:Danger of serious damage to health by prolonged exposure.
R36/37/38:Irritating to eyes, respiratory system and skin .
R24/25:Toxic in contact with skin and if swallowed .
R11:Highly Flammable. | [Safety Statements ]
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
1325 | [WGK Germany ]
3
| [F ]
21 | [TSCA ]
Yes | [HazardClass ]
4.1 | [PackingGroup ]
III | [HS Code ]
29280090 |
| Hazard Information | Back Directory | [Chemical Properties]
White to pale yellow lumps | [Uses]
Starting material for preparing BOC-azide, a reagent to introduce the BOC amino protection. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 82, p. 2725, 1960 DOI: 10.1021/ja01496a018
Chemical and Pharmaceutical Bulletin, 18, p. 217, 1970 DOI: 10.1248/cpb.18.217 | [Purification Methods]
Distil it in a Claisen flask with a water or oil bath at ca 80o. After a couple of drops have distilled, the carbazate is collected as an oil which solidifies to a snow white solid. It can be crystallised with 90% recovery from a 1:1 mixture of pet ether (b 30-60o) and pet ether (b 60-70o). [Carpino et al. Org Synth Coll Vol V 166 1973, Caprino et al. Org Synth 44 20 1964, Beilstein 3 IV 175.] |
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