DIMETHYL 5-BROMOISOPHTHALATE synthesis
- Product Name:DIMETHYL 5-BROMOISOPHTHALATE
- CAS Number:51760-21-5
- Molecular formula:C10H9BrO4
- Molecular Weight:273.08
23351-91-9
161 suppliers
$6.00/1g
51760-21-5
187 suppliers
$6.00/1g
Yield:51760-21-5 89%
Reaction Conditions:
with sulfuric acid;sodium hydrogencarbonate in methanol
Steps:
3 [Preparation of dimethyl 5-bromoisophthalate from 5-bromoisophthalic acid]
[Preparation of dimethyl 5-bromoisophthalate from 5-bromoisophthalic acid] Into a 500 ml flask equipped with a stirrer and a Dimroth condenser, 110 g of 5-bromoisophthalic acid obtained above, 500 ml of methanol and 10 g of a concentrated sulfuric acid were placed and the resultant mixture was heated under the refluxing condition for 6 hours. After the reaction mixture was cooled by being left standing, the cooled mixture was added dropwise to 1 liter of distilled water and the obtained mixture was neutralized with a 5% by weight aqueous solution of sodium hydrogencarbonate. The formed precipitates were separated by filtration and washed twice with 2 liters of distilled water. The obtained white solid substance was dried at 50?C under a reduced pressure for 2 days and 109 g (0.4 moles) of dimethyl 5-bromoisophthalate was obtained (the yield: 89%).
References:
SUMITOMO BAKELITE CO., LTD. EP1346975, 2003, A1
99-27-4
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51760-21-5
187 suppliers
$6.00/1g
23351-91-9
161 suppliers
$6.00/1g
74-88-4
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51760-21-5
187 suppliers
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67-56-1
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23351-91-9
161 suppliers
$6.00/1g
51760-21-5
187 suppliers
$6.00/1g
67-56-1
771 suppliers
$7.29/5ml-f
121-91-5
597 suppliers
$6.00/10g
1459-93-4
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$11.00/100g
51760-21-5
187 suppliers
$6.00/1g