天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->2346-74-9

2346-74-9

2346-74-9 Structure

2346-74-9 Structure
IdentificationMore
[Name]

6-CHLORO-9-METHYLPURINE
[CAS]

2346-74-9
[Synonyms]

NSC 4948
AKOS BBS-00003131
IFLAB-BB F1371-0159
OTAVA-BB BB7216640145
6-CHLORO-9-METHYLPURINE
9-METHYL-6-CHLOROPURINE
6-CHLORO-9-METHYL-9H-PURINE
9H-Purine, 6-chloro-9-methyl-
8a-(2,4-dimethylphenyl)-3,4,7,8-tetrahydro-2H-pyrrolo[2,1-b][1,3]oxazin-6-one
[Molecular Formula]

C6H5ClN4
[MDL Number]

MFCD00127840
[Molecular Weight]

168.58
[MOL File]

2346-74-9.mol
Chemical PropertiesBack Directory
[Appearance]

Pale Yellow Solid
[Melting point ]

129-134oC
[Boiling point ]

321.7±45.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

Chloroform (Slightly), Ethyl Acetate (Slightly)
[form ]

Solid
[pka]

1.26±0.10(Predicted)
[color ]

Off-White
[Usage]

A useful synthetic intermediate
[CAS DataBase Reference]

2346-74-9(CAS DataBase Reference)
Hazard InformationBack Directory
[Chemical Properties]

6-CHLORO-9-METHYLPURINE is Pale Yellow Solid
[Uses]

6-CHLORO-9-METHYLPURINE is a useful synthetic intermediate
[Uses]

A useful synthetic intermediate.
[Synthesis Reference(s)]

Journal of the American Chemical Society, 79, p. 490, 1957 DOI: 10.1021/ja01559a069
[Synthesis]

6-Chloropurine

87-42-3

Iodomethane

74-88-4

6-CHLORO-9-METHYLPURINE

2346-74-9

To a solution of 6-chloro-9H-purine (3.00 g, 20.0 mmol) in anhydrous THF (100 mL) cooled to 0°C was added 60% sodium hydride (1.2 g, 30.0 mmol) in portions. The reaction mixture was stirred in an ice bath for 0.5 h. Then iodomethane (2.82 g, 20.0 mmol) was slowly added and stirring was continued for 1 h at room temperature. After completion of the reaction, the mixture was diluted with 100 mL of water and extracted with ethyl acetate (30 mL x 3). The organic layers were combined, dried with anhydrous magnesium chloride and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography with the eluent being a 20% ethyl acetate/petroleum ether solvent mixture. The white solid product 9-methyl-6-chloropurine was obtained in 74.6% (2.50 g) yield. The product was analyzed by ESI-MS, m/z: 169.1 [M + H]+; 1H NMR (300 MHz, DMSO-d6) δ: 3.72 (3H, s, CH3), 8.72 (1H, s, H-purine), 9.15 (1H, s, H-purine).

[References]

[1] European Journal of Medicinal Chemistry, 2014, vol. 89, p. 581 - 596
[2] Synthesis, 2007, # 2, p. 219 - 224
[3] Angewandte Chemie - International Edition, 2018, vol. 57, # 18, p. 5134 - 5138
[4] Angew. Chem., 2018, vol. 130, # 18, p. 5228 - 5232,5
[5] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 1, p. 139 - 149
Spectrum DetailBack Directory
[Spectrum Detail]

6-CHLORO-9-METHYLPURINE(2346-74-9)1HNMR
2346-74-9 suppliers list
Company Name: Capot Chemical Co.,Ltd.
Tel: +8613336195806 , +8613336195806
Website: www.capot.com
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051 , +8613580539051
Website: www.yuhengpharm.com
Company Name: Blocksynth Pharmaceutical Technology Co.,Ltd
Tel: 0086-19817745290; +8619817745290 , +8619817745290
Website: http://www.blocksynth.com/
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
Tel: +86-0571-88938639 +8617705817739 , +8617705817739
Website: www.dycnchem.com/
Company Name: NewCan Biotech Limited
Tel: +86-0571-86912261 +8613735419629 , +8613735419629
Website: https://www.newcanbio.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: GIHI CHEMICALS CO.,LIMITED
Tel: +8618058761490 , +8618058761490
Website: www.gihichem.com/
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
Website: www.leapchem.com
Company Name: Wuhan Fortuna Chemical Co.,Ltd
Tel: +86-2759207851; +8618007136271 , +8618007136271
Website: http://m.approvedhomemanagement.com/manufacturer/Wuhan%20Fortuna%20chemical/
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-6139-8061 +86-86-13650506873 , +86-86-13650506873
Website: http://www.chemdad.com/
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Website: http://www.amadischem.com
Company Name: ROSEWA HOLDING GROUP CO.,LIMITED
Tel: +86-023-62871537
Website: m.approvedhomemanagement.com/ShowSupplierProductsList31018/0_EN.htm
Company Name: ALS INDIA LIFE SCIENCES  
Tel: +91-8977036379
Website: www.alsindialife.com
Company Name: Mainchem Co., Ltd.  
Tel: +86-0592-6210733
Website: https://www.mainchem.com
Company Name: Chemwill Asia Co.,Ltd.  
Tel: 86-21-51086038
Website: www.chemwill.com
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532
Website: www.jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: m.approvedhomemanagement.com/ShowSupplierProductsList13285/0_EN.htm
Tags:2346-74-9 Related Product Information
7306-68-5 2004-06-0 2004-07-1 87-42-3 2346-74-9

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.