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ChemicalBook--->CAS DataBase List--->186610-89-9

186610-89-9

186610-89-9 Structure

186610-89-9 Structure
IdentificationBack Directory
[Name]

CIVENTICHEM CV-409
[CAS]

186610-89-9
[Synonyms]

CIVENTICHEM CV-409
[Molecular Formula]

C20H19N3O2
[MDL Number]

MFCD08443934
[MOL File]

186610-89-9.mol
[Molecular Weight]

333.38
Chemical PropertiesBack Directory
[Boiling point ]

649.1±55.0 °C(Predicted)
[density ]

1.340±0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 50 mg/mL (149.98 mM)
[form ]

Orange to red crystalline solid.
[pka]

12.93±0.20(Predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

SU4984 is a protein tyrosine kinase inhibitor, with an IC50 of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits platelet-derived growth factor receptor, and insulin receptor. SU4984 can be used for the research of cancer[1][2][3].
[IC 50]

FGFR1: 10-20 μM (IC50)
[References]

[1] Mohammadi M, et, al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science. 1997 May 9;276(5314):955-60. DOI:10.1126/science.276.5314.955
[2] Ma Y, et, al. Indolinone derivatives inhibit constitutively activated KIT mutants and kill neoplastic mast cells. J Invest Dermatol. 2000 Feb;114(2):392-4. DOI:10.1046/j.1523-1747.2000.00888.x
Spectrum DetailBack Directory
[Spectrum Detail]

CIVENTICHEM CV-409(186610-89-9)1HNMR
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