| Identification | Back Directory | [Name]
AG 825 | [CAS]
149092-50-2 | [Synonyms]
AG 825
Zinc02572484
TYRPHOSTIN C15
AG 825 USP/EP/BP
TYRPHOSTIN AG 825
AG 825 (Tyrphostin AG 825)
AG 825 - CAS 149092-50-2 - Calbiochem
4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE
5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE
3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-
2-Propenamide
2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-
(E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE
Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide | [Molecular Formula]
C19H15N3O3S2 | [MDL Number]
MFCD01074971 | [MOL File]
149092-50-2.mol | [Molecular Weight]
397.47 |
| Hazard Information | Back Directory | [Uses]
A selective ErbB2 inhibitor | [Uses]
AG 825 is a selective ErbB2 (Neu) inhibitor and apoptosis inducer. | [Definition]
ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth
factor receptor antagonist. | [Biological Activity]
Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells. | [storage]
Store at -20°C |
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Synchem OHG
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