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ChemicalBook >> CAS DataBase List >> 12(S)-HPETE

12(S)-HPETE

12(S)-HPETE price.
  • $131 - $1030
  • Product name: 12(S)-HPETE
  • CAS: 71774-10-2
  • MF: C20H32O4
  • MW: 336.47
  • EINECS:
  • MDL Number:MFCD00063585
  • Synonyms:12S-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;12(S)-HYDROPEROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;12(S)-HPETE;(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid;(5Z,8Z,10E,12S,14Z)-12-Hydroperoxyicosa-5,8,10,14-tetraenoic acid;12(S)-Hydroperoxy-eicosatetraenoic acid;(5Z,8Z,10Z,12S,14Z)-12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
6 prices
Brand
  • AHH
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 0.0001g
  • 100μg
  • 250μg
  • ManufacturerAHH
  • Product numberMT-14827
  • Product description12(S)-Hpete 98%
  • Packaging0.0001g
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number44570
  • Product description12(S)-HpETE ≥98%
  • Packaging25μg
  • Price$131
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number44570
  • Product description12(S)-HpETE ≥98%
  • Packaging50μg
  • Price$246
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number44570
  • Product description12(S)-HpETE ≥98%
  • Packaging100μg
  • Price$466
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number44570
  • Product description12(S)-HpETE ≥98%
  • Packaging250μg
  • Price$1030
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH456410
  • Product description12(S)-HPETE
  • Packaging50μg
  • Price$225
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-14827 12(S)-Hpete 98% 0.0001g $298 2021-12-16 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 25μg $131 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 50μg $246 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 100μg $466 2024-03-01 Buy
Cayman Chemical 44570 12(S)-HpETE ≥98% 250μg $1030 2024-03-01 Buy
TRC H456410 12(S)-HPETE 50μg $225 2021-12-16 Buy

Properties

Boiling point :518.0±50.0 °C(Predicted)
Density :1.013±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form :Liquid.
pka :4.75±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.

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