Human Fetuin B Protein, His Tag
分子別名(Synonym)
FETUB,Fetuin-B,16G2,Gugu
表達區(qū)間及表達系統(tǒng)(Source)
Human Fetuin B, His Tag (FEB-H52H7) is expressed from human 293 cells (HEK293). It contains AA Cys 16 - Pro 382 (Accession # AAH69670 ).
Predicted N-terminus: Cys 16
蛋白結構(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 42.4 kDa. The protein migrates as 53-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
胎球蛋白B(FETUB)是哺乳動物胎球蛋白家族的第二個成員,也被稱為胎球蛋白樣蛋白IRL685、16G2和Gugu,在肝臟和睪丸中表達,含有2個半胱氨酸蛋白酶抑制劑胎球蛋白-B型結構域。FETUB是卵子受精所需的蛋白酶抑制劑。FETUB還需要在受精前防止透明帶過早硬化,可能是通過抑制ASTL的蛋白酶活性,ASTL是一種介導ZP2切割并引發(fā)透明帶硬化的蛋白酶(通過相似性)。作為一種肝臟來源的血漿蛋白,FETUB對受精至關重要。
關鍵字: Fetuin B;Fetuin B蛋白;Fetuin B重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。