中文名：印苦楝內酯
英文名：Nimbolide
中文別名：印苦楝內酯|(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(3-呋喃基)-2a,5a,6,6a,8,9,9a,10a,10b,10c-十氫-2a,5a,6a,7-四甲基-2,5-二羰基-2H,5H-環(huán)戊二烯并[d']萘并[1,8-bc:2,3-b']二呋喃-6-乙酸甲基酯
英文別名：Nimbolide|25990-37-8|NSC309909|methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate|Methyl 2-[(1R,2S,4R,6R,9R,10S,11R,15R,18R)-6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-di
純度：≥97%
貨號：N275747
包裝：25mg、5mg、1mg
Cas號：25990-37-8
存儲溫度：-20°C儲存,干燥
產(chǎn)品介紹：
Nimbolide is a limonoid tetranortriterpenoid with an α,β-unsaturated ketone system and a δ-lactone ring.
添加Biochem/physiol ActionsNimbolide exhibits anti-malarial, anti-bacterial, and anti-cancer activities. It has been shown to induce apoptosis in osteosarcoma cells and inhibits cell migration of these cells by modulating the expression of integrin αvβ5. In human renal carcinoma cells, nimbolide induced cell cycle arrest, DNA damage, and apoptosis.
Nimbolide is a triterpene isolated from Azadirachta indica. It has been shown to modulate autophagy and apoptosis in pancreatic cancer.
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關鍵字： 印苦楝內酯;(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-(3-呋喃基)-2a,5a,6,6a,8,9,9a,10a,10b,10c-十氫-2a,5a,6a,7-四甲基-2,5-二羰基-2H,5H-環(huán)戊二烯并[d']萘并[1,8-bc:2,3-b']二呋喃-6-乙酸甲基酯;Nimbolide;25990-37-8
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