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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Sulfonamides and synergist>Trimethoprim
Trimethoprim
  • Trimethoprim

Trimethoprim NEW

Price $45
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-26

Product Details

Product Name: Trimethoprim CAS No.: 738-70-5
Purity: 99.81% Supply Ability: 10g
Release date: 2025/05/26

Product Introduction

Bioactivity

NameTrimethoprim
DescriptionTrimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
In vivoTrimethoprim acts by interfering with the bacterial dihydrofolate reductase, inhibiting the synthesis of tetrahydrofolic acid. This inhibition causes a deficiency in nucleotides essential for bacterial DNA replication, which in some instances leads to cell death due to thymineless death.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 55 mg/mL (189.45 mM), Sonication is recommended.
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
Keywordsurinary tract infections | Trimethoprim | Thymidylate synthase | tetrahydrofolate | Shigellosis | RNASynthesis | RNA Synthesis | reductase | protein | Pneumocystis pneumonia | NSC106568 | NSC 106568 | NIH-204 | NIH204 | metabolism | Inhibitor | inhibit | Influenza Virus | Hsps | folate | DNASynthesis | DNA Synthesis | dihydrofolate | DHFR | Bacterial | Antimicrobial | Antifolate | Antibiotic | aggregation
Inhibitors RelatedNeomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Urethane | Sulfamethoxazole sodium | Guanidine hydrochloride | Doxycycline | Thymidine | Isoeugenol | Dimethyl sulfoxide
Related Compound LibrariesBioactive Compound Library | Anti-Cancer Clinical Compound Library | Natural Product Library | Anti-Viral Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bitter Compound library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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