CT-2584 NEW
| Price | $333 | $790 | $1120 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-02 |
Product Details
| Product Name: CT-2584 | CAS No.: 166981-13-1 |
| Purity: 99.23% | Supply Ability: 10g |
| Release date: 2025/05/02 |
Product Introduction
Bioactivity
| Name | CT-2584 |
| Description | CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types. CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA. |
| In vitro | CT-2584 (0-7 μM, 3 days) was toxic to ECV304, to which B/1 cells were highly resistant. [5]；Toxicity was observed in human hepatocellular carcinoma Alex 0 cells at 3.5 mmol/L CT-2584 and Alex 0.5 cells at 2.0 mmol/L CT-2584. 24 hours later, cytotoxicity and decreased HBsAg (hepatitis B surface antigen) secretion were observed, even at lower concentrations. [6] |
| In vivo | Daily intraperitoneal injection of 25 mg/kg CT-2584 for three consecutive days was tolerated in SCID mice. When higher doses (50 mg/kg) were attempted, the animals died due to drug-related peritonitis. [6] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | CT-2584 |
| Inhibitors Related | Sodium Thiocyanate | Acetylcysteine | Imeglimin hydrochloride | L-Ascorbic acid | α-Vitamin E | Ammonium sulfate | Glucosamine | D-(+)-Glucono-1,5-lactone | Coenzyme Q10 | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Naringenin |
| Related Compound Libraries | NF-κB Signaling Compound Library | Bioactive Compound Library | Anti-Obesity Compound Library | Anti-Ovarian Cancer Compound Library | Mitochondria-Targeted Compound Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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