CT-179 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-22 |
Product Details
| Product Name: CT-179 | CAS No.: 1996636-69-1 |
| Purity: 98.67% | Supply Ability: 10g |
| Release date: 2025/07/22 |
Product Introduction
Bioactivity
| Name | CT-179 |
| Description | CT-179 is a potent and selective inhibitor of oligodendrocyte transcription factor 2 (OLIG2), reduces tumor cell proliferation and induces apoptosis, and enhances efficacy when used in combination with radiotherapy and other agents, showing potential in the treatment of medulloblastoma and glioblastoma. |
| In vitro | Methods: Daoy, UW228, and Med-813 MB cells were treated with CT-179 (0.01-10 μM, 7 days), and cell viability was determined by MTT assay. Results: CT-179 showed activity in all three cell lines, with IC50 values ??of 143.6 nM, 285.4 nM, and 985.2 nM, respectively. [1] |
| In vivo | Methods: CT-179 (50 mg/kg, ip, twice weekly for 2 weeks) was combined with RT (8 Gy, 2 Gy fractions) to treat immunocompromised NOD rag γ (NRG) mice implanted with orthotopic Daoy-luci (SHH-MB) to investigate whether it exhibits similar antitumor activity against human MB in vivo. Results: Animals treated with CT-179 + RT had significantly slower progression and significantly delayed tumor growth in the brain and spinal cord; CT-179 combined with RT significantly prolonged EFS. [1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | IMG7289 | IMG 7289 | CT-179 | CT 179 | Bomedemstat ditosylate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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