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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Angiogenesis>HIF inhibitor>2-METHOXYESTRADIOL
2-METHOXYESTRADIOL
  • 2-METHOXYESTRADIOL

2-METHOXYESTRADIOL

Price $540
Package 100gram
Min. Order: 100gram
Supply Ability: 20 tons
Update Time: 2024-09-25

Product Details

Product Name: 2-METHOXYESTRADIOL CAS No.: 362-07-2
Min. Order: 100gram Purity: 99% HPLC
Supply Ability: 20 tons Release date: 2024/09/25

CAS:362-07-2

MF: C19H26O3

MW:302.41

Melting Point:188-190°C

Boiling Point:464.4±45.0 °C(Predicted)

Density:1.178±0.06 g/cm3(Predicted)


Product Description

2-methoxyestradiol (2-methoxyestradiol), 2-methoxyestradiol (2ME2) was first found in the urine of pregnant women, and it was previously believed to be the end product of estradiol metabolism. not much. Laboratory data indicate that 2-methoxyestradiol is a substrate of P450CYP1A2, especially CYP3A4; it is also extensively metabolized by uridine diphosphate glucuronyltransferase (UDP-glucuChemicalbookronosyltransferase). CYP1A2, CYP3A4, and uridine diphosphate glucuronyltransferase are widely present in the duodenum, small intestine, and liver, but these enzymes are less distributed in the large intestine. Therefore, oral 2-methoxyestradiol must be released as far as possible in the large intestine, so that more of the absorbed part can enter the systemic circulation. Therefore, it is very urgent to study to improve the druggability of 2-methoxyestradiol.


Company Profile Introduction

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

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  • Since: 2022-10-21
  • Address: Wanda global centur, Wuhan China
INQUIRY

+86-13627115097
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