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ChemicalBook > Product Catalog >Organic Chemistry >Hydrocarbons and derivatives >Hydrocarbon nitrification >3-Chloro-4-fluoronitrobenzene

3-Chloro-4-fluoronitrobenzene

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Products Intro: Product Name:3-Chloro-4-fluoronitrobenzene
CAS:350-30-1
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CAS:350-30-1
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CAS:350-30-1
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3-Chloro-4-fluoronitrobenzene Basic information
Synthesis
Product Name:3-Chloro-4-fluoronitrobenzene
Synonyms:2-chloro-1-fluoro-4-nitro-benzen;Benzene, 2-chloro-1-fluoro-4-nitro-;Benzene,2-chloro-1-fluoro-4-nitro-;1-CHLORO-2-FLUORO-5-NITROBENZENE;3-CHLORO-4-FLUORONITROBENZENE;4-FLUORO-3-CHLORONITROBENZENE;3-chloro-4-fluorobenzene;3-CHLORO-4-FLUORONITROANILINE
CAS:350-30-1
MF:C6H3ClFNO2
MW:175.54
EINECS:206-499-3
Product Categories:Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Fluorinated benzene series
Mol File:350-30-1.mol
3-Chloro-4-fluoronitrobenzene Structure
3-Chloro-4-fluoronitrobenzene Chemical Properties
Melting point 40-42 °C(lit.)
Boiling point 227-232°C
density 1.61
Fp >230 °F
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Light yellow to Green
BRN 1944997
CAS DataBase Reference350-30-1(CAS DataBase Reference)
NIST Chemistry Reference3-Chloro-4-fluoronitrobenzene(350-30-1)
EPA Substance Registry System3-Chloro-4-fluoronitrobenzene (350-30-1)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-37/38-41-36/37/38-20/21/22
Safety Statements 26-39-36/37/39
RIDADR 2811
WGK Germany 3
RTECS CZ0720000
Hazard Note Irritant
HazardClass 6.1
PackingGroup III
HS Code 29049090
MSDS Information
ProviderLanguage
3-Chloro-4-fluoronitrobenzene English
SigmaAldrich English
ACROS English
ALFA English
3-Chloro-4-fluoronitrobenzene Usage And Synthesis
SynthesisIn certain instances, when both chloro and nitro may act as a leaving group, a surprising selectivity of one over the other is observed, for example chloro-2,5- dinitrobenzene was converted to 4-fluoro-3-chloronitrobenzene.
3-Chloro-4-fluoronitrobenzene
Chemical Propertieswhite to light yellow crystal powder
Uses2-Chloro-1-fluoro-4-nitrobenzene has been used in synthesis of:
  • benzoimidolones on Ameba resin
  • methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate
Uses2-Chloro-1-fluoro-4-nitrobenzene is an intermediate used in synthesis of benzoimidolones on Ameba resin and methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate.
Synthesis Reference(s)The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o
Synthetic Communications, 21, p. 505, 1991 DOI: 10.1080/00397919108016776
General Description2-Chloro-1-fluoro-4-nitrobenzene undergoes reduction in the presence of Mo(CO)6 and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) under microwave irradiation to yield a mixture of 3-chloro-4-fluoroaniline and 3-chloro-4-ethoxyaniline.
Tag:3-Chloro-4-fluoronitrobenzene(350-30-1) Related Product Information
4-Fluoronitrobenzene 1-Fluoro-2-nitrobenzene 1-Chloro-3-nitrobenzene Cyhalothrin Epichlorohydrin 4-CHLORO-3-FLUORONITROBENZENE 4-(3-Chloropropyl)morpholine Isovanillin Benzonitrile, 5-methoxy-4-[3-(4-morpholinyl)propoxy]-2-nitro- 4-Chloro-3-fluoroaniline Benzonitrile, 2-amino-5-methoxy-4-[3-(4-morpholinyl)propoxy]- 3-Chloro-2-fluoroaniline λ-Cyhalothrin Benzonitrile, 5-hydroxy-4-methoxy-2-nitro- Nitrobenzene 4-Chloronitrobenzene Difluorochloromethane 2-Nitrochlorobenzene

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