人參皂甙 Rc
| 中文名稱 | 人參皂甙 Rc |
|---|---|
| 中文同義詞 | 人參皂苷RC(人參皂甙RC);GINSENOSIDE RC 人參皂苷RC;人參皂苷RC;人參皂甙RC;人參皂苷 RC, 來(lái)源于人參;人叁皂甙RC;人參皂莢RB1;人參皂莢RC |
| 英文名稱 | Ginsenoside Rc |
| 英文同義詞 | Ginsenoside Rc, froM Panax ginseng;NSC 310104;20-[(6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;GINSENOSIDE FROM GINSENG ROOT (PANAX*QUI NQUEFOLIUM;20-[(6-O-alpha-L-Arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12b-hydroxydammar-24-en-3b-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside;GINSENOSIDE RC WITH HPLC;arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-;glucopyranosyl- |
| CAS號(hào) | 11021-14-0 |
| 分子式 | C53H90O22 |
| 分子量 | 1079.27 |
| EINECS號(hào) | 234-253-5 |
| 植物來(lái)源 | 人參 |
| 相關(guān)類別 | 植提;小分子抑制劑，天然產(chǎn)物;有機(jī)硼化合物;小分子抑制劑;中藥對(duì)照品;標(biāo)準(zhǔn)品;對(duì)照品,標(biāo)準(zhǔn)品;分析標(biāo)準(zhǔn)品;植物提取物;對(duì)照品;植提標(biāo)準(zhǔn)品;中藥標(biāo)準(zhǔn)品;化學(xué)試劑;生化試劑-其他化學(xué)試劑;標(biāo)準(zhǔn)品-中藥標(biāo)準(zhǔn)品;Saponins;Biochemicals Found in Plants;Isoprenoid/terpenoid;Nutrition Research;Ginsenoside series;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;分析試劑標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品，對(duì)照品;三萜;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品;分析試劑-對(duì)照品;標(biāo)準(zhǔn)品-對(duì)照品;生物化工;原料 |
| Mol文件 | 11021-14-0.mol |
| 結(jié)構(gòu)式 |  |
人參皂甙 Rc 性質(zhì)
| 熔點(diǎn) | 199～201℃ |
|---|---|
| 沸點(diǎn) | 1128.3±65.0 °C(Predicted) |
| 密度 | 1.42±0.1 g/cm3(Predicted) |
| 儲(chǔ)存條件 | Sealed in dry,2-8°C |
| 溶解度 | DMSO（微量）、甲醇（微量）、吡啶（微量） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 12.85±0.70(Predicted) |
| 顏色 | 白色至淺黃色 |
| 生物來(lái)源 | plant root (Panax ginseng) |
| 穩(wěn)定性 | 吸濕性 |
| LogP | 5.100 (est) |
| CAS 數(shù)據(jù)庫(kù) | 11021-14-0(CAS DataBase Reference) |
|
TNF-α
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IL-1β
|
Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances γ-aminobutyric acid (GABA) receptor A (GABA A )-mediated ion channel currents. Ginsenoside Rc enhances GABA-mediated ion currents in oocytes expressing the GABA A receptor. Ginsenoside Rc significantly inhibits the expression of macrophage-derived cytokines, such as TNF-α and IL-1β. Ginsenoside Rc also markedly suppresses the activation of TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling in activated RAW264.7 macrophages, human synovial cells, and HEK293 cells. Ginsenoside Rc exerts its anti-inflammatory actions by suppressing TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling. Ginsenoside Rc suppresses the nuclear translocation of phospho-ATF-2 and phospho-FRA-1, whereas the translocation of p65 at its peak time points (30 and 60 min) is not decreased by Ginsenoside Rc treatment. Ginsenoside Rc regulates the expression of the proinflammatory cytokine TNF-α, which is produced by macrophages, by suppressing AP-1 activation.
安全信息
| 提供商 | 語(yǔ)言 |
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英文
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| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2025/02/08 | HY-N0042 | 人參皂甙 Rc Ginsenoside Rc | 11021-14-0 | 5mg | 650元 |
| 2025/02/08 | HY-N0042 | 人參皂甙 Rc Ginsenoside Rc | 11021-14-0 | 10mg | 1100元 |