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?? ??:
4159-77-7
???:
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???(??):
??????;??????
???:
ROSE BENGAL LACTONE
???(??):
Solvent Red 141;ROSE BENGAL LACTONE;4’,5’,7’-tetraiodo-droxy-2;C.I.Solvent Red 141:C.I.45440:1;4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein;spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy;4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one;4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
CBNumber:
CB8331887
???:
C20H4Cl4I4O5
??? ??:
973.67
MOL ??:
4159-77-7.mol
MSDS ??:
SDS

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???
280 °C (dec.)(lit.)
?? ??
room temp
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741.8±60.0 °C(Predicted)
??
2.96±0.1 g/cm3(Predicted)
?? ?? (pKa)
7.03±0.20(Predicted)
??? ??
powder
??
pink to red
?? ??(λmax)
557 nm
ε (????)
≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm
EPA
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  • ?? ? ???? ?? (GHS)
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????? 26-37/39
WGK ?? 3
????(GHS): GHS hazard pictograms
?? ?: Warning
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?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
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P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

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Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol.

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Bluish-pink powder. Soluble in water.

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Biological stain; colorant for inks, cellulosics, foods, cosmetics, medicine (diagnostic aid).

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will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide.

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