4-Nitrophenyl chloroformate
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4-Nitrophenyl chloroformate ??
- ???
- 77-79 °C(lit.)
- ?? ?
- 159-162 °C19 mm Hg(lit.)
- ??
- 1.5719 (rough estimate)
- ???
- 1.6000 (estimate)
- ???
- >110°C
- ?? ??
- 2-8°C
- ???
- ???, ?????, ???, ??? ? ??? ?????.
- ??? ??
- ?????? ???
- ??
- ???? ???-????
- ???
- ??? ????
- ??
- Lachrymatory
- BRN
- 518127
- ???
- ????. ???, ?? ???? ????. ?? ??.
- CAS ??????
- 7693-46-1(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | C,T,Xi,F | ||
|---|---|---|---|
| ?? ???? ?? | 34-36/37-23/24/25-41-36/37/38-11-67-36 | ||
| ????? | 26-36/37/39-45-38-28A-36-16-27 | ||
| ????(UN No.) | UN 3261 8/PG 2 | ||
| WGK ?? | 3 | ||
| F ?????? | 19-21 | ||
| ?? ?? ?? | Toxic/Corrosive/Lachrymator | ||
| TSCA | Yes | ||
| ?? ?? | 8 | ||
| ???? | II | ||
| HS ?? | 29159020 | ||
| ???? ?? | 2000-3-1451 |
4-Nitrophenyl chloroformate C??? ??, ??, ??
??? ??
Cream solid??
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane. It is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules.?? ??
4-Nitrophenyl chloroformate is used as:A coupling agent to link the drug molecule with the polyrotaxane carrier molecule.As an activated ester reagent that enables the covalent coupling of a peptide onto a macromer, such as oligo(poly(ethylene glycol) fumarate) (OPF).??
4-Nitrophenyl chloroformate, also known as p-nitrophenyl chloroformate, is a coupling agent used in the synthesis of ureas, carbamates, and carbonates. It is also used as a building block in solid-phase peptide synthesis (SPPS) to obtain altered side chain functionalities in peptides.4-Nitrophenyl chloroformate ?? ?? ? ???
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Temozolomide
Z-GLY-ONP
Z-LEU-ONP
FMoc-?-Cit-PAB-PNP
Mc-Val-Cit-PABC-PNP
5-???-2-???????
Temozolomide Impurity
Carbonic acid, 4-nitrophenyl [4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl ester
cyclohexyl (4-nitrophenyl) carbonate
4-(Phenoxycarbonylamino)benzeneboronic acid pinacol ester, 95%
N-??-N-??-O-(4-?????)??????
4-Nitrophenyl 4-(pyridin-2-yldisulfanyl)benzyl carbonate
4-Nitrophenyl chloroformate ?? ??
???( 510)?? ??
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4-Nitrophenyl chloroformate ?? ??:
4-??????? 4-?????? ???? ??????-1-????????? ????? ?????? 4-??????? ????? ?????? 4-????? 4-??????
Methyl 4-bromobenzoate
4-Nitrophenylacetic acid
4-Nitrobenzenesulfonyl chloride
4-Nitrobenzonitrile
4-(tert-Butyl)benzyl mercaptan
4-Hydroxyphenylacetic acid
4-Hydroxyphenethyl alcohol
4-Nitrophenyl phosphate bis(cyclohexylammonium) salt
4-Nitrobenzyl chloroformate
4-Bromophenylacetic acid