ChemicalBook >?? ???? >??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)???????

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)???????

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? ??? ???

?? ??:: 22235-81-0

???:: ??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)???????

???(??):: ??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)???????

???:: endo-(±)-8-aza-8-isopropylbicyclo[3.2.1]oct-3-yl (hydroxymethyl)phenylacetate

???(??):: YB-M2;Ipratropium Impurity E;N-Isopropylnoratropine;N-DesMethyl IpratropiuM;Ipratropium Bromide Impurity 13;Ipratropium Bromide EP Impurity E;N-Isopropylnoratropine, 10 mM in DMSO;NIsopropylnoratropine,N Isopropylnoratropine;Ipratropium Bromide Impurity 13(Ipratropium EP Impurity E);Ipratropium Bromide EP Impurity E (N-Isopropyl Noratropine)

CBNumber:: CB6932642

???:: C19H27NO3

??? ??:: 317.42

MOL ??:: 22235-81-0.mol

?? ?? 64

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? ??

???: 112-114°C

?? ?: 448.8±45.0 °C(Predicted)

??: 1.15±0.1 g/cm3(Predicted)

?? ??: Refrigerator

???: ?????(?? ???), ???(?? ???)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 14.12±0.10(Predicted)

??: ???? ?? ?????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??		P264, P270, P301+P312, P330, P501

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P330	?? ?????.
P501	...? ??? / ??? ?? ???.

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? C??? ??, ??, ??

??? ??

Off-White to Pale Orange Solid

??

N-Isopropyl Noratropine is a Noratropine derivative, an intermediate in the production of Ipratropium.

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? ?? ?? ? ???

???

????? ??-8-?????-8-??????[3.2.1]??-3-? Acetyltropylic chloride ?? ?????? ???? ???

?? ??

??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? ?? ??

???( 64)?? ??

???	??	???	??	?? ?	??
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??-(±)-8-??-8-?????????[3.2.1]??-3-?(??????)??????? ?? ??:

(endo,anti)-(±)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide DL-TROPIC ACID Tropic acid Ipratropium bromide 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran A-(HYDROXYMETHYL)BENZENACETIC ACID METHYL ESTER Benzenepropanoic acid, b-oxo-a-phenyl-, methyl ester IpratropiuM BroMide IMpurity F (Mixture of DiastereoMers) endo-8-isopropyl-8-azabicyclo[3.2.1]octan-3-ol Atropine Impurity 4 Tropinone Atropine littorine (S)-Tropic acid Pseudotropine (1R,2R,4S,5S,7s,9S)-7-(((S)-3-hydroxy-2-phenylpropanoyl)oxy)-9-methyl-9-propyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium Atropine-d5 Atropine sulfate

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