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2-?????

2-?????
2-????? ??? ???
?? ??:
141-90-2
???:
2-?????
???(??):
2-?????;2-??????
???:
2-Thiouracil
???(??):
TU;2-thioxo-2,3-dihydropyriMidin-4(1H)-one;Thiouracil;2-TU;DERACIL;Nobilen;THIURACIL;NSC 19473;Thiouraci;tiouracyl
CBNumber:
CB5769908
???:
C4H4N2OS
??? ??:
128.15
MOL ??:
141-90-2.mol
MSDS ??:
SDS

2-????? ??

???
>300 °C (lit.)
?? ??
600kg/m3
??
1.368 (estimate)
???
1.7000 (estimate)
?? ??
Store below +30°C.
???
7.9g/L
?? ?? (pKa)
pKa 7.46 (Uncertain)
??? ??
?? ??? ??
??
???? ?????
???? ??
synthetic
???
0.5g/L
?? ??(λmax)
271nm(H2O)(lit.)
Merck
14,9366
BRN
112227
InChIKey
ZEMGGZBWXRYJHK-UHFFFAOYSA-N
CAS ??????
141-90-2(CAS DataBase Reference)
IARC
2B (Vol. Sup 7, 79) 2001
NIST
2-Thiouracil(141-90-2)
EPA
Thiouracil (141-90-2)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,T
?? ???? ?? 40-45-20/21/22
????? 36/37-53-45
WGK ?? 3
RTECS ?? YR1575000
?? ?? ?? 570°C
TSCA Yes
HS ?? 29335995
?? ?? ??? 141-90-2(Hazardous Substances Data)
???? ?? KE-10757
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H351 ?? ??? ??? ??? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??) ??? ?? ?? 2 ?? P201, P202, P281, P308+P313, P405,P501
??????:
P281 ???? ?? ???? ?????
NFPA 704
0
1 0

2-????? MSDS


4-Hydroxy-2-mercaptopyrimidine

2-????? C??? ??, ??, ??

??? ??

white to cream fine crystalline powder

??

2-Thiouracil has been used in the synthesis and characterization of silver colloid and film substrates and their applications in surface-enhanced Raman scattering (SERS)

??

ChEBI: A nucleobase analogue that is uracil in which the oxo group at C-2 is replaced by a thioxo group.

Safety Profile

Moderately toxic by ingestion. Human teratogenic effects by unspecified routes: developmental abnormalities of the central nervous system, craniofacial area, and endocrine system. Human reproductive effects by unspecified route: effects on newborn, including viabllity index changes. Experimental teratogenic effects. Other experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. Used in the treatment of hyperthyroidism, angina pectoris, and congestive heart failure. See also MERCAPTANS and KETONES.

Purification Methods

Crystallise 2-thiouracil from water or EtOH. [Beilstein 24 H 323, 24 I 315, 24 II 171, 24 III/IV 1237.]

2-????? ?? ?? ? ???

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2-????? ?? ??

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2-????? ?? ??:

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