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DBCO-PEG4-maleimide

DBCO-PEG4-maleimide ??? ???
?? ??:
1480516-75-3
???:
DBCO-PEG4-maleimide
???(??):
DBCO-PEG4-MAL;DBCO-dPEG??-MAL;DBCO-PEG4-Maleimid;DBCO-PEG4-maleimide;DBCO-NHCO-PEG4-BMPA;DBCO-NH-PEG4-Maleimide;DBCO-NHCO-PEG4-NH-Maleimide;DBCO-PEG4-Maleimide (CCT-A108P);Dibenzocyclooctyne-PEG4-maleimide;DBCO-PEG4-Maleimide?Chemical Structure
CBNumber:
CB52925269
???:
C36H42N4O9
??? ??:
674.74
MOL ??:
1480516-75-3.mol

DBCO-PEG4-maleimide ??

?? ?
965.2±65.0 °C(Predicted)
??
1.31±0.1 g/cm3(Predicted)
?? ??
-20°C
???
Soluble in DMSO, DCM, DMF
?? ?? (pKa)
15.01±0.46(Predicted)
??? ??
?? ??
??
Colorless to light yellow
InChIKey
VVFZXPZWVJMYPX-UHFFFAOYSA-N
SMILES
N1(CCC(NCCOCCOCCOCCOCCC(=O)NCCC(N2CC3=CC=CC=C3C#CC3=CC=CC=C23)=O)=O)C(=O)C=CC1=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312 ???? ??? ????(??)? ??? ????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.

DBCO-PEG4-maleimide C??? ??, ??, ??

??

Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules.
Applications Include:

DBCO-PEG4-maleimide ?? ?? ? ???

???

?? ??


DBCO-PEG4-maleimide ?? ??

???( 79)?? ??
??? ?? ??? ?? ?? ? ??
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DBCO-PEG4-maleimide ?? ??:

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