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EVERNIC ACID

EVERNIC ACID ??? ???

?? ??:: 537-09-7

???:: EVERNIC ACID

???(??):: Nsc81164;EVERNIC ACID;LECANORIC ACID METHYL ETHER;EVERNIC ACID YELLOW CRYSTALS;orsellinic acid 4-everninate;Wln: qr cq E1 dvovr bq F1 do1;4-[(4-methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylic acid;6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylate;6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylicacid;2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-.beta.-resorcylate

CBNumber:: CB4395269

???:: C17H16O7

??? ??:: 332.3

MOL ??:: 537-09-7.mol

MSDS ??:: SDS

?? ?? 65

EVERNIC ACID ??

???: 166-167°C

???: DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml

??? ??: ??? ??

??: White to off-white

LogP: 5.030 (est)

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???? ??	KE-23326

EVERNIC ACID C??? ??, ??, ??

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Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC₅₀ = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC₅₀ = 77.3 μM).

EVERNIC ACID ?? ?? ? ???

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2,4-DIHYDROXY-6-METHYLBENZOIC ACID

EVERNIC ACID ?? ??

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EVERNIC ACID ?? ??:

LECANORIC ACID DIFFRACTIC ACID GYROPHORIC ACID EVERNIC ACID thielavin B STICTIC ACID LOBARIC ACID thielavin A PS 990 EVERNIC ACID EVERNIC ACID(RG) EVERNIC ACID(REAGENT / STANDARD GRADE) thielocin B3 RARECHEM AN KA 2323 RARECHEM AN KC 2319 RARECHEM AN KB 2328 RARECHEM AN KD 2338

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