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ACT 080803

ACT 080803 ??? ???

?? ??:: 1433875-21-8

???:: ACT 080803

???(??):: ACT 080803;Masitectan impurity;Macititan impurity 01;Macitentan Impurity 01;Macitentan N-Despropylaminosulfonyl Impurity;5-(4-bromophenyl)-6-(2-((5-bromopyrimidin-2-yl);5-(4-Bromophenyl)-6-(2-((5-bromopyrimidin-2-yl)oxy)ethoxy)pyrimidin-4-amine;4-Pyrimidinamine, 5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-;5-(4-Bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-ylamine

CBNumber:: CB22716118

???:: C16H13Br2N5O2

??? ??:: 467.11

MOL ??:: 1433875-21-8.mol

?? ?? 57

ACT 080803 ??

?? ?: 607.5±65.0 °C(Predicted)

??: 1.722±0.06 g/cm3(Predicted)

???: DMSO(?? ???), ???(?? ???, ??)

?? ?? (pKa): 3.00±0.10(Predicted)

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ACT 080803 C??? ??, ??, ??

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Despropylaminosulfonyl Macitentan is an impurity of Macitentan (M105005); a dual orally active endothelin receptor antagonist used for pulmonary arterial hypertension.

ACT 080803 ?? ?? ? ???

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ACT 080803 ?? ??

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???	??	???	??	?? ?	??
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5221	58
Guangzhou CATO Research Chemicals Inc.	+86-020-81960175-617 +8615602392859	Intermediate@cato-chem.com	China	6335	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	ORDERS@QCSRM.COM	China	24342	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	4872	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7552	61
Shanghai ChuangYan Chemical Technology Co., Ltd.	021-11111111 11111111111	546919421@qq.com	China	3367	55

ACT 080803 ?? ??:

(???????)?? ??-???? 2-(4-BROMOPHENYL)-PROPANEDIOIC ACID, 1,3-MDIETHYL ESTER macitentan 5-Bromo-2-chloropyrimidine Macitentan Impurity 11 Macitentan Impurity 2 Macitentan Impurity 13 Macitentan Impurity 17 5-(4-Bromophenyl)-4,6-dichloropyrimidine SulfaMide, N-[5-(4-broMophenyl)-6-chloro-4-pyriMidinyl]-N'-propyl- 4(1H)-PyriMidinone, 5-(4-broMophenyl)-6-hydroxy- CarbaMic acid, N-[(propylaMino)sulfonyl]-, phenylMethyl ester FORMAMIDINE HYDROCHLORIDE Macitentan impurity A Macitentan Impurity 14 ACT 373898 Macitentan Impurity 10

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