A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.
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ChEBI: An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.
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Colorless to dark red liquid.
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Very sensitive to exposure to air and light. Turns red to brown on exposure to light and air. . Slightly soluble in water.
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Phenetidine reacts vigorously with powerful oxidizers.
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Phenetidine is combustible.
Safety Profile
Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
