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(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン

(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 化學(xué)構(gòu)造式
78821-43-9
CAS番號(hào).
78821-43-9
化學(xué)名:
(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン
別名:
(24R)-24-エピブラッシノリド;(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン;(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-24-メチル-6,7-セコ-6,7-エポキシ-6-オキソ-5α-コレスタン;24-エピブラッシノリド;(22R,23R)-2α,3α,22,23-テトラヒドロキシ-7-オキサ-B-ホモ-5α-エルゴスタン-6-オン;24-エピブラシノリド;24-epi-ブラッシノリド;24-epi-ブラシノライド;(1S,2R,4R,5S,7S,11S,12S,15R,16S)-15-[(2S,3R,4R,5R)-3,4-ジヒドロキシ-5,6-ジメチルヘプタン-2-イル]-4,5-ジヒドロキシ-2,16-ジメチル-9-オキサテトラシクロ[9.7.0.02,7.012,16]オクタデカン-8-オン
英語(yǔ)名:
Epibrassinolide
英語(yǔ)別名:
24-EPIBRASSINOLIDE;Epibrassinolide;BP55;B1105;CS-1258;Epibrassinolide;Brassinolide,BR;24R-BRASSINOLIDE;4-Epicastasterone;EPIBRASSINOLIDE (EBI)
CBNumber:
CB8361275
化學(xué)式:
C28H48O6
分子量:
480.68
MOL File:
78821-43-9.mol
MSDS File:
SDS

(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 物理性質(zhì)

融點(diǎn) :
256°C
沸點(diǎn) :
633.7±55.0 °C(Predicted)
比重(密度) :
1.141±0.06 g/cm3(Predicted)
貯蔵溫度 :
-20°C
溶解性:
クロロホルム(微量)、酢酸エチル(微量)
外見(jiàn) :
個(gè)體
酸解離定數(shù)(Pka):
14.27±0.70(Predicted)
色:
ホワイトからオフホワイト
EPAの化學(xué)物質(zhì)情報(bào):
3H-Benz[c]indeno[5,4-e]oxepin-3-one, 10-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-trimethylhexyl]hexadecahydro-5,6-dihydroxy-7a,9a-dimethyl-, (3aS,5S,6R,7aR,7bS,9aS,10R,12aS,12bS)- (78821-43-9)
安全性情報(bào)
  • リスクと安全性に関する聲明
  • 危険有害性情報(bào)のコード(GHS)
Rフレーズ  22-36/37/38
Sフレーズ  22-36/37/39-45
WGK Germany  3
HSコード  29372900
絵表示(GHS) GHS hazard pictograms
注意喚起語(yǔ)
危険有害性情報(bào)
コード 危険有害性情報(bào) 危険有害性クラス 區(qū)分 注意喚起語(yǔ) シンボル P コード
H302 飲み込むと有害 急性毒性、経口 4 警告 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 強(qiáng)い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 呼吸器への刺激のおそれ 特定標(biāo)的臓器毒性、単回暴露; 気道刺激性 3 警告 GHS hazard pictograms
注意書(shū)き
P261 粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。
P271 屋外または換気の良い場(chǎng)所でのみ使用すること。
P280 保護(hù)手袋/保護(hù)衣/保護(hù)眼鏡/保護(hù)面を著用するこ と。

(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 価格 もっと(4)

メーカー 製品番號(hào) 製品説明 CAS番號(hào) 包裝 価格 更新時(shí)間 購(gòu)入
富士フイルム和光純薬株式會(huì)社(wako) W01TRCE582000
Epi Brassinolide, 90%
78821-43-9 10mg ¥132600 2024-03-01 購(gòu)入
富士フイルム和光純薬株式會(huì)社(wako) W01TRCE582000
Epi Brassinolide, 90%
78821-43-9 100mg ¥672700 2023-06-01 購(gòu)入
Sigma-Aldrich Japan E1641 エピブラシノリド ≥85%
Epibrassinolide ≥85%
78821-43-9 2mg ¥39200 2024-03-01 購(gòu)入
Sigma-Aldrich Japan E1641 エピブラシノリド ≥85%
Epibrassinolide ≥85%
78821-43-9 10mg ¥93300 2024-03-01 購(gòu)入

(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 化學(xué)特性,用途語(yǔ),生産方法

説明

Epibrassinolide is a brassinosteroid that can be isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. Epibrassinolide is also reported to be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It has also been shown to protect neuronal PC12 cells from 1-methyl-4-phenylpyridinium-induced oxidative stress and consequent apoptosis in dopaminergic neurons.

化學(xué)的特性

White Solid

化學(xué)的特性

The solubility of epibrassinolide in ethanol and DMSO is approximately 3 mg/ml and approximately 5 mg/ml in DMF.

使用

Epibrassinolide has been used:
  • in Murashige and Skoog (MS) medium to study the cotyledon and shoot length response of Cappelle-Desprez (rht8) and RIL6 (Rht8) plants towards it
  • in callus-inducing medium for callus induction
  • to induce the expression of the gene leaf inclination 2 (LC2) in rice sampling

代謝経路

Two isomeric metabolites, 25-b- and 26-b-D- glucopyranosyloxy-24-epi-brassinolides, are formed in tomato cell suspension cultures with endogenously applied 24-epi-brassinolide. The two-step metabolic process involves hydroxylation of the side chain at C25 and C26, respectively, followed by glucosidation of the newly formed hydroxyl groups. The ratio between both metabolites is altered by in vivo treatment of the cell cultures with various cytochrome P-450-specific inhibitors, indicating the involvement of two different enzyme systems. Biosynthetically prepared 25-hydroxy-24-epi-brassinolide, reapplied to the cell cultures, is exclusively glucosylated at the 25- hydroxyl group, strongly suggesting regiospecificity of the corresponding glucosyltransferase.

(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品


(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン 生産企業(yè)

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(22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン  スペクトルデータ(MS)


78821-43-9((22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン)キーワード:


  • 78821-43-9
  • 22R,23R,24R-2ALPHA,3ALPHA,22,28-TETRAHYDROXY-B-HOMO-7-OXA-5ALPHA-ERGOSTA-6-ONE
  • (22R,23R,24R)-2-ALPHA,3-ALPHA,22,23-TETRAHYDROXY-24-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE
  • 22R,23R,24R-2A,3A,22,23-TETRAHYDROXY-B-HOMO-7-OXA-5A-ERGOSTAN-6-ONE
  • 24R-BRASSINOLIDE
  • 2-ALPHA,3-ALPHA,22R,23R,-TETRAHYDROXY-B-HOMO-7-OXA-5-ALPHA-ERGOSTAN-6-ONE
  • 2-ALPHA,3-ALPHA,22R,23R-TETRADHYDROXY-24R-METHYL-B-HOMO-7-OXA-5-ALPHA-CHOLESTAN-6-ONE
  • 5-ALPHA-CHOLESTANE-B-HOMO-7-OXA-24-BETA-METHYL-2-ALPHA, 3-ALPHA, 22-ALPHA, 23-ALPHA-TETROL-6-ONE
  • EPIBRASSINOLIDE 98% (HPLC)
  • 22R,23R,24R-2α,3α,22,23-Tetrahydroxy-B-homo-7-oxa-5α-ergostan-6-one
  • (22R,23R)-2α,3α,22,23-Tetrahydroxy-7-oxa-B-homo-5α-ergostan-6-one
  • (22R,23R,24R)-2α,3α,22,23-Tetrahydroxy-24-methyl-6,7-seco-6,7-epoxy-6-oxo-5α-cholestane
  • (24R)-24-Epibrassinolide
  • EPIBRASSINOLIDE (EBI)
  • Epibrassinolide,22R,23R,24R-2α,3α,22,23-Tetrahydroxy-B-homo-7-oxa-5α-ergostan-6-one
  • Epibrassinolide
  • (22R/S,23R/S,24R)-2alpha,3alpha,22,23-Tetrahydroxy-beta-home-7-oxa-5-alpha-ergostan-6-one
  • (1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-1-[(1S,2R,3R,4R)-2,3-Dihydroxy-1,4,5-triMethylhexyl]hexadecahydro-8,9-dihydroxy-10a,12a-diMethyl-6H-benz[c]indeno[5,4-e]oxepin-6-one
  • Epibrassinolide(24-Epibrassinolide)
  • 4-Epicastasterone
  • 6H-Benz[c]indeno[5,4-e]oxepin-6-one,1-[(1S,2R,3R,4R)-2,3-dihydroxy-1,4,5-triMethylhexyl]hexadecahydro-8,9-dihydroxy-10a,12a-diMethyl-,(1R,3aS,3bS,6aS,8S,9R,10aR,10bS,12aS)-
  • EPIBRASSINOLIDE, >=85%
  • CS-1258
  • 24-EPIBRASSINOLIDE;B1105;BP55
  • B1105
  • BP55
  • 24-Epibrassinolide (Brassinolide)
  • 2,4-Epibrassinolide (Brassinosteriod)
  • 24-EPIBRASSINOLIDE
  • Brassinolide,BR
  • 5α-CHOLESTANE-B-HOMO-7-OXA-24β-METHYL-2α, 3α, 22α, 23α-TETROL-6-ONE
  • (24R)-24-エピブラッシノリド
  • (22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-B-ホモ-7-オキサ-5α-エルゴスタン-6-オン
  • (22R,23R,24R)-2α,3α,22,23-テトラヒドロキシ-24-メチル-6,7-セコ-6,7-エポキシ-6-オキソ-5α-コレスタン
  • 24-エピブラッシノリド
  • (22R,23R)-2α,3α,22,23-テトラヒドロキシ-7-オキサ-B-ホモ-5α-エルゴスタン-6-オン
  • 24-エピブラシノリド
  • 24-epi-ブラッシノリド
  • 24-epi-ブラシノライド
  • (1S,2R,4R,5S,7S,11S,12S,15R,16S)-15-[(2S,3R,4R,5R)-3,4-ジヒドロキシ-5,6-ジメチルヘプタン-2-イル]-4,5-ジヒドロキシ-2,16-ジメチル-9-オキサテトラシクロ[9.7.0.02,7.012,16]オクタデカン-8-オン
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