1-BENZYLPIPERIDINE-4-CARBONITRILE
- CAS No.
- 62718-31-4
- Chemical Name:
- 1-BENZYLPIPERIDINE-4-CARBONITRILE
- Synonyms
- OTAVA-BB 1369796;1-N-BENZYL-4-CYANOPIPERIDINE;1-Benzyl-4-piperidinecarbonitrile;1-BENZYLPIPERIDINE-4-CARBONITRILE;1-Benzylpiperidine-4-carbonitrile ,97%;4-Piperidinecarbonitrile, 1-(phenylMethyl)-
- CBNumber:
- CB51511616
- Molecular Formula:
- C13H16N2
- Molecular Weight:
- 200.28
- MDL Number:
- MFCD01540574
- MOL File:
- 62718-31-4.mol
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
HS Code | 29333990 |
1-BENZYLPIPERIDINE-4-CARBONITRILE price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B288840 | 1-Benzyl-4-cyanopiperidine | 62718-31-4 | 1g | $250 | 2021-12-16 | Buy |
TRC | B288840 | 1-Benzyl-4-cyanopiperidine | 62718-31-4 | 2.5g | $455 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB140419 | 1-Benzylpiperidine-4-carbonitrile | 62718-31-4 | 10g | $540 | 2021-12-16 | Buy |
Matrix Scientific | 074344 | 1-Benzylpiperidine-4-carbonitrile 95+% | 62718-31-4 | 5g | $899 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0073444 | 1-BENZYLPIPERIDINE-4-CARBONITRILE 95.00% | 62718-31-4 | 1G | $958.65 | 2021-12-16 | Buy |
1-BENZYLPIPERIDINE-4-CARBONITRILE Chemical Properties,Uses,Production
Uses
1-Benzylpiperidine-4-carbonitrile is an intermediate in organic synthesis and pharmaceutical intermediate for lab R&D.
Synthesis
Step 1 Preparation of intermediate 1-benzyl-4-carbonylamide piperidine
To piperidine-4-carboxamide (16.5 g, 0.13 mol ) and K2CO3 (35.6 g, 0.26 mol) in EtOH (350 ml) was added benzyl bromide (22.0 g, 0.13 mol) And heated to reflux for 3 h, cooled to room temperature and filtered. The filtrate was evaporated in vacuo and H2O (200ml) was added. The aqueous layer was extracted with CH2Cl2 (3×150ml), the organic layers were combined, and Na2SO4Dry and filter. The solvent was evaporated in vacuo to give the product as a white solid (20.0 g, 71.0%).
Step 2 Preparation of intermediate 1-benzyl-4-cyanopiperidine
1-benzyl-4-carbonylamide piperidine (20.0 g, 91.7 mmol) Mixed with P2O5 (16.92, 119.2 mmol) and heated under argon at 180-200°C for 3 h, cooled to room temperature and added H2O (150 ml). The aqueous solution was basified by the careful addition of K2CO3 and then extracted with EtOAc (3× 150 ml). The organic extract was dried over Na2SO4, filtered and the solvent evaporated in vacuo to give a yellow oil (16.7 g, 90.9%).
1-BENZYLPIPERIDINE-4-CARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29865 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49985 | 58 |
Sichuan Biosynce Pharmatech Co., Ltd. | +8619950309693 | diane@biosynce.com | China | 4871 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from 1-BENZYLPIPERIDINE-4-CARBONITRILE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2019-09-02 | 1-BENZYLPIPERIDINE-4-CARBONITRILE
62718-31-4
|
US $1.00 / KG | 1KG | 98% | 1lg; 2kg; 5kg; 10kg; 100kg | Career Henan Chemical Co |
-
- 1-BENZYLPIPERIDINE-4-CARBONITRILE
62718-31-4
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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