H-LYS-GLN-ALA-GLY-ASP-VAL-OH
- CAS No.
- 80755-87-9
- Chemical Name:
- H-LYS-GLN-ALA-GLY-ASP-VAL-OH
- Synonyms
- KQAGDV;LYS-GLN-ALA-GLY-ASP-VAL;Fibrinogen γ-chain fragmen;Fibrinogen γ-chain fragment;H-LYS-GLN-ALA-GLY-ASP-VAL-OH;L-Valine, L-lysyl-L-glutaminyl-L-alanylglycyl-L-α-aspartyl-
- CBNumber:
- CB4109969
- Molecular Formula:
- C25H44N8O10
- Molecular Weight:
- 616.66
- MDL Number:
- MFCD00133515
- MOL File:
- 80755-87-9.mol
- MSDS File:
- SDS
H-LYS-GLN-ALA-GLY-ASP-VAL-OH price More Price(1)
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Chemical Properties,Uses,Production
Uses
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].
Definition
ChEBI: Lys-Gln-Ala-Gly-Asp-Val is an oligopeptide.
Biochem/physiol Actions
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is a cell adhesion peptide used to study adhesion of platelets to neutrophils via the integrin glycoproteins gpIIb/IIIa.
References
[1] Dong CL, et al. The cytocompatability of polyhydroxyalkanoates coated with a fusion protein of PHA repressor protein (PhaR) and Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) polypeptide. Biomaterials. 2012 Mar;33(9):2593-9. DOI:10.1016/j.biomaterials.2011.12.020
[2] Mann BK, et al. Tethered-TGF-beta increases extracellular matrix production of vascular smooth muscle cells. Biomaterials. 2001 Mar;22(5):439-44. DOI:10.1016/s0142-9612(00)00196-4
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-LYS-GLN-ALA-GLY-ASP-VAL-OH Suppliers
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Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
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GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
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