3-Bromo-L-tyrosine
- CAS No.
- 38739-13-8
- Chemical Name:
- 3-Bromo-L-tyrosine
- Synonyms
- H-Tyr(3-Br)-OH;L-3-Bromotyrosine;3-Bromo-L-tyrosine;L-Tyrosine, 3-bromo-;3-bromo-L-tyrosine (L-type);(S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid;(2S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid
- CBNumber:
- CB1966684
- Molecular Formula:
- C9H10BrNO3
- Molecular Weight:
- 260.08
- MDL Number:
- MFCD09836116
- MOL File:
- 38739-13-8.mol
| Melting point | 247-248 °C |
|---|---|
| Boiling point | 402.8±45.0 °C(Predicted) |
| Density | 1.710±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Sparingly), DMSO (Heated), Methanol (Heated) |
| form | Solid |
| pka | 2.21±0.20(Predicted) |
| color | White to Pale Brown |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
3-Bromo-L-tyrosine price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B688565 | 3-Bromo-L-tyrosine | 38739-13-8 | 1g | $175 | 2021-12-16 | Buy |
| AK Scientific | 5012AB | 3-Bromo-L-tyrosine | 38739-13-8 | 10g | $222 | 2021-12-16 | Buy |
| AK Scientific | J11160 | 3-Bromo-L-tyrosine | 38739-13-8 | 5g | $238 | 2021-12-16 | Buy |
| Activate Scientific | AS40828 | (S)-2-Amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid 97% ee | 38739-13-8 | 5G | $247 | 2021-12-16 | Buy |
| ChemScene | CS-W019172 | 3-?Bromo-?L-?tyrosine 98.33% | 38739-13-8 | 25g | $277 | 2021-12-16 | Buy |
3-Bromo-L-tyrosine Chemical Properties,Uses,Production
Uses
3-Bromo-L-tyrosine is used in the preparation and synthesis of polyclonal antibodies that work against brominated protein related allergic responses and afflictions. Also effective in asthma control a nd prediction in children.
Definition
ChEBI: 3-bromo-L-tyrosine is a bromoamino acid comprising an L-tyrosine core with a bromo- substituent ortho to the hydroxy group on the benzene ring. It is a bromoamino acid, a L-tyrosine derivative, a member of bromobenzenes and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a 3-bromo-L-tyrosine zwitterion.
Synthesis
60-18-4
38739-13-8
The general procedure for the synthesis of (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propionic acid from L-tyrosine was as follows: reaction of D- or L-tyrosine (1.0 g) with N-bromosuccinimide (NBS, 1.5 g, 8.3 mmol) in anhydrous THF (15 mL). The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the solution was concentrated under reduced pressure and purified by rapid column chromatography on silica gel to afford D- or L-3-bromotyrosine (100 mg). The product was analyzed by electrospray mass spectrometry (positive ion mode) and showed m/z 260/262 (1:1).1H NMR (500 MHz, CD3OD) data were as follows: δH 7.46 (s, H-2); 7.13 (d, J = 8.2 Hz, H-6); 6.91 (d, J = 8.2 Hz, H-5); 3.97 (m, H-8); 3.22 (dd, J = 4.6, 14.6 Hz, H-7a); 3.03 (dd, J = 7.8, 14.6 Hz, H-7b).
References
[1] Amino Acids, 2013, vol. 44, # 2, p. 529 - 532
[2] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[3] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[4] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[5] Patent: US2007/259883, 2007, A1. Location in patent: Page/Page column 8
3-Bromo-L-tyrosine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15221 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9629 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 19957148339; | market18@leapchem.com | China | 24727 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 |
View Lastest Price from 3-Bromo-L-tyrosine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-03 | 3-Bromo-L-tyrosine
38739-13-8
|
US $6.60 / KG | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
-
- 3-Bromo-L-tyrosine
38739-13-8
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co
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