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ChemicalBook >> CAS DataBase List >>tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

CAS No.
1198408-35-3
Chemical Name:
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
Synonyms
tert-Butyl 4-(6-aminopyridin-3-yl);4-(6-Amino-3-pyridyl)-1-Boc-piperidine;4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;ert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate ISO 9001:2015 REACH;6-amino-3',4',5',6'-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylicacidtert-butylester
CBNumber:
CB12594133
Molecular Formula:
C15H23N3O2
Molecular Weight:
277.36
MDL Number:
MFCD11111266
MOL File:
1198408-35-3.mol
Last updated:2025-07-24 18:13:40

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Properties

Boiling point 422.8±45.0 °C(Predicted)
Density 1.134±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 6.80±0.26(Predicted)
Appearance Off-white to light yellow Solid
InChI InChI=1S/C15H23N3O2/c1-15(2,3)20-14(19)18-8-6-11(7-9-18)12-4-5-13(16)17-10-12/h4-5,10-11H,6-9H2,1-3H3,(H2,16,17)
InChIKey UGJYTOMOCDGLRS-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(C2=CC=C(N)N=C2)CC1

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B811320 tert-Butyl4-(6-Aminopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3 100mg $265 2021-12-16 Buy
AK Scientific 3427DH Tert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3 1g $667 2021-12-16 Buy
Ambeed A331079 tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95% 1198408-35-3 5g $747 2021-12-16 Buy
A1 Biochem Labs 6594354 tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95% 1198408-35-3 2.5g $900 2021-12-16 Buy
Crysdot CD11333802 tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95+% 1198408-35-3 5g $1337 2021-12-16 Buy
Product number Packaging Price Buy
B811320 100mg $265 Buy
3427DH 1g $667 Buy
A331079 5g $747 Buy
6594354 2.5g $900 Buy
CD11333802 5g $1337 Buy

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Chemical Properties,Uses,Production

Synthesis

tert-butyl 4-(6-nitropyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate

1231930-22-5

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate

1198408-35-3

In a 500 mL round-bottomed flask, tert-butyl 4-(6-nitropyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate (4.9 g, 16.0 mmol, 1.00 equiv.) was dissolved in a solvent mixture of ethanol (300 mL) and ethyl acetate (75 mL) and palladium carbon (1.32 g, 1.24 mmol, 0.0773 equiv.) was added. The reaction mixture was displaced twice with hydrogen and then stirred overnight under a hydrogen atmosphere (using a hydrogen balloon). The completion of the reaction was confirmed by LC/MS analysis. The reaction mixture was purged with nitrogen and filtered through a diatomaceous earth pad, which was washed several times with ethyl acetate. The colorless filtrate and washings were combined, dichloromethane was added and the solution was evaporated to dryness. Dichloromethane was added again and the solution was concentrated under vacuum to give the target product tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate in quantitative yield. (M + H)+ = 278 m/z.

References

[1] Patent: WO2013/24078, 2013, A1. Location in patent: Page/Page column 57; 58
[2] Patent: CN106608879, 2017, A. Location in patent: Paragraph 0268-0269; 0273-0274
[3] Patent: WO2014/83026, 2014, A1. Location in patent: Page/Page column 26; 47-48
[4] Patent: CN105622638, 2016, A. Location in patent: Paragraph 0181
[5] Patent: US2018/297995, 2018, A1. Location in patent: Paragraph 0046; 0051; 0052

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Suppliers

Global( 82)Suppliers
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career henan chemical co
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13417589054 trendseenbio@gmail.com China 11681 58

View Lastest Price from tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate pictures 2025-07-25 tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
US $0.00 / kg 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate pictures 2025-06-25 tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate pictures 2020-03-06 tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
US $1.00 / KG 1KG 97%-99.9% 100kg Career Henan Chemical Co

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Spectrum

tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate tert-Butyl 4-(6-aminopyridin-3-yl) 4-(6-Amino-3-pyridyl)-1-Boc-piperidine 1-Piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester ert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate ISO 9001:2015 REACH 6-amino-3',4',5',6'-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylicacidtert-butylester 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 1198408-35-3