tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
- CAS No.
- 1198408-35-3
- Chemical Name:
- tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
- Synonyms
- tert-Butyl 4-(6-aminopyridin-3-yl);4-(6-Amino-3-pyridyl)-1-Boc-piperidine;4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;ert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(6-amino-3-pyridinyl)-, 1,1-dimethylethyl ester;tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate ISO 9001:2015 REACH;6-amino-3',4',5',6'-tetrahydro-2'H-[3,4']bipyridinyl-1'-carboxylicacidtert-butylester
- CBNumber:
- CB12594133
- Molecular Formula:
- C15H23N3O2
- Molecular Weight:
- 277.36
- MDL Number:
- MFCD11111266
- MOL File:
- 1198408-35-3.mol
Boiling point | 422.8±45.0 °C(Predicted) |
---|---|
Density | 1.134±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C(protect from light) |
pka | 6.80±0.26(Predicted) |
Appearance | Off-white to light yellow Solid |
InChI | InChI=1S/C15H23N3O2/c1-15(2,3)20-14(19)18-8-6-11(7-9-18)12-4-5-13(16)17-10-12/h4-5,10-11H,6-9H2,1-3H3,(H2,16,17) |
InChIKey | UGJYTOMOCDGLRS-UHFFFAOYSA-N |
SMILES | N1(C(OC(C)(C)C)=O)CCC(C2=CC=C(N)N=C2)CC1 |
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | B811320 | tert-Butyl4-(6-Aminopyridin-3-yl)piperidine-1-carboxylate | 1198408-35-3 | 100mg | $265 | 2021-12-16 | Buy |
AK Scientific | 3427DH | Tert-butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate | 1198408-35-3 | 1g | $667 | 2021-12-16 | Buy |
Ambeed | A331079 | tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95% | 1198408-35-3 | 5g | $747 | 2021-12-16 | Buy |
A1 Biochem Labs | 6594354 | tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95% | 1198408-35-3 | 2.5g | $900 | 2021-12-16 | Buy |
Crysdot | CD11333802 | tert-Butyl4-(6-aminopyridin-3-yl)piperidine-1-carboxylate 95+% | 1198408-35-3 | 5g | $1337 | 2021-12-16 | Buy |
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Chemical Properties,Uses,Production
Synthesis

1231930-22-5

1198408-35-3
In a 500 mL round-bottomed flask, tert-butyl 4-(6-nitropyridin-3-yl)-5,6-dihydropyridine-1(2H)-carboxylate (4.9 g, 16.0 mmol, 1.00 equiv.) was dissolved in a solvent mixture of ethanol (300 mL) and ethyl acetate (75 mL) and palladium carbon (1.32 g, 1.24 mmol, 0.0773 equiv.) was added. The reaction mixture was displaced twice with hydrogen and then stirred overnight under a hydrogen atmosphere (using a hydrogen balloon). The completion of the reaction was confirmed by LC/MS analysis. The reaction mixture was purged with nitrogen and filtered through a diatomaceous earth pad, which was washed several times with ethyl acetate. The colorless filtrate and washings were combined, dichloromethane was added and the solution was evaporated to dryness. Dichloromethane was added again and the solution was concentrated under vacuum to give the target product tert-butyl 4-(6-aminopyridin-3-yl)piperidine-1-carboxylate in quantitative yield. (M + H)+ = 278 m/z.
References
[1] Patent: WO2013/24078, 2013, A1. Location in patent: Page/Page column 57; 58
[2] Patent: CN106608879, 2017, A. Location in patent: Paragraph 0268-0269; 0273-0274
[3] Patent: WO2014/83026, 2014, A1. Location in patent: Page/Page column 26; 47-48
[4] Patent: CN105622638, 2016, A. Location in patent: Paragraph 0181
[5] Patent: US2018/297995, 2018, A1. Location in patent: Paragraph 0046; 0051; 0052
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Preparation Products And Raw materials
tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
Shanghai zaiqi biology technology co., ltd | +86-21-54824098 13817598959 | sales@chemzq.com | CHINA | 136 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7921 | 58 |
Chemsigma International Co., Ltd. | +8618136843612 | info@chemsigma.com | China | 1729 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
View Lastest Price from tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-07-25 | tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-06-25 | tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
|
US $1.10 / g | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
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2020-03-06 | tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
-
- tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
- US $1.10 / g
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- tert-butyl 4-(6-aMinopyridin-3-yl)piperidine-1-carboxylate
1198408-35-3
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co
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