Thiazovivin
|
|
|
- CAS-Nr.
- 1226056-71-8
- Englisch Name:
- Thiazovivin
- Synonyma:
- TZV;CS-1925;Thiazovivin;Thiazovivin (Tzv);Thiazovivin, >=98%;Thiazovivin USP/EP/BP;Thiazovivin, 10 mM in DMSO;Thiazovivin, ROCK inhibitor;Thiazovivin (DMSO solution), Rho kinase inhibitor;N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide
- CBNumber:
- CB92512070
- Summenformel:
- C15H13N5OS
- Molgewicht:
- 311.36
- MOL-Datei:
- 1226056-71-8.mol
|
Thiazovivin Eigenschaften
- Dichte
- 1.379
- storage temp.
- -20°C
- L?slichkeit
- DMSO: soluble20mg/mL, clear
- pka
- 13.87±0.46(Predicted)
- Aggregatzustand
- powder
- Farbe
- , white to beige to brown
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
- InChI
- InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
- InChIKey
- DOBKQCZBPPCLEG-UHFFFAOYSA-N
- SMILES
- S1C=C(C(NCC2=CC=CC=C2)=O)N=C1NC1C=CN=CN=1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
|
|
| R-S?tze: |
22 |
|
|
| WGK Germany |
3 |
|
|
| HS Code |
2934100090 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
Thiazovivin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A compound that improves the survival of human embryonic stem cells (hESCs) upon trypsinization. In combination with ALK5 (TGFβ receptor) inhibitor SB-431542 and MEK inhibitor PD-0325901 (P217450), Thiazovivin promotes the transformation of fibroblasts into stem cells with a 200-fold efficiency over the classic method
Biochem/physiol Actions
Thiazovivin is an inhibitor of Rho associated coiled-coil containing protein kinase (ROCK). In vitro studies prove that thiazovivin is efficient in stimulating better morphology, expression of ionic transporter and protein involved in cell adhesion.
Thiazovivin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Thiazovivin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 194)Lieferanten
1226056-71-8()Verwandte Suche:
- N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide Thiazovivin
- Thiazovivin
N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide
- Thiazovivin, >=98%
- N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide
- Thiazovivin
- N-(Phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide
- N-Benzyl-2-(4-pyrimidinylamino)-1,3-thiazole-4-carboxamide
- CS-1925
- Thiazovivin (Tzv)
- 4-Thiazolecarboxamide, N-(phenylmethyl)-2-(4-pyrimidinylamino)-
- Thiazovivin USP/EP/BP
- TZV
- Thiazovivin (DMSO solution), Rho kinase inhibitor
- Thiazovivin, ROCK inhibitor
- Thiazovivin, 10 mM in DMSO
- 1226056-71-8
- 226056-71-8
- Inhibitors
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Sulfur & Selenium Compounds
