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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Struktur
196961-43-0
CAS-Nr.
196961-43-0
Englisch Name:
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
Synonyma:
CD 3254;CD3254,CD-3254;CD3254, 10 mM in DMSO;3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid;2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
CBNumber:
CB72518841
Summenformel:
C24H28O3
Molgewicht:
364.48
MOL-Datei:
196961-43-0.mol

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Eigenschaften

Schmelzpunkt:
165 - 167°C
Siedepunkt:
508.0±50.0 °C(Predicted)
Dichte
1.108±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
4.61±0.10(Predicted)
Farbe
White to Off-White

Sicherheit

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CD3254 is a selective agonist of the retinoid X receptors (RXRs; EC50 = ~10 nM for human RXRβ) that is without effect on retinoic acid receptors (RARs). It stimulates the recruitment of the nuclear receptor interaction domain of the TRAP220 coactivator to RXRα/RARβ heterodimers in vitro. CD3254 also enhances the recruitment of the PPARγ coactivator 1α, PGC-1α, to RXRα/PPARγ heterodimers.

Verwenden

CD 3254 is a potent RXR agonist.

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 52)Lieferanten
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
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TargetMol Chemicals Inc. 		+1-781-999-5354;
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Aladdin Scientific
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
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Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
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196961-43-0()Verwandte Suche:

  • 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
  • CD 3254
  • 2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
  • CD3254,CD-3254
  • CD3254, 10 mM in DMSO
  • 196961-43-0
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