GMDP Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

N-acetyl-β-D-glucosaminyl-( 1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine was launched in Russia for hospital-related infections, psoriasis, cervical precancerous lesions and ophthalmic keratitis caused by herpes. It was found to be less pyrogenic than MDP, the minimally active component of Freund's complete adjuvant. While chemical synthesis is possible, a less laborious method (3 steps) involves the enzymatic degradation of a bacterial peptidoglycan. GDMP is orally active with a low toxicity that acts as an adjuvant to highly purified protein antigens to stimulate the induction of CD8^* T-cell response. It was also able to reduce the levels of TNF-α, IL-1α and hypoglycemia induced by LPS administration and to inhibit systemic response to endotoxin.

Originator

Peptech (Australia)

Trademarks

Likopid

GMDP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GMDP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18194	56
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9980	55
Nantong Hanfang Biotechnology Co. , Ltd.	hanfangpharma@126.com; 18616537568	hanfangpharma@126.com	China	29964	58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd.,	18915873328	296197970@qq.com	China	11055	58

70280-03-4()Verwandte Suche:

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• d-alpha-glutamine,n-(n-acetyl-4-o-(2-(acetylamino)-2-deoxy-beta-d-glucopyrano
• glucosaminylmuramyldipeptide
• n-acetyl-beta-glucosaminyl-(1-4)-n-acetylmuramyl-l-alanyl-d-isoglutamine
• n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
• n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine
• syl)muramoyl)-l-alanyl-
• 4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace
• N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io
• 4-(2-ACETAMIDO-2-DEOXY-B-D- &
• 4-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-n-acetylmuramyl-l-ala-d-glu amide
• d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine
• D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
• GMDP
• N-ACETYL-D-GLUCOSAMINYL-(BETA1,4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
• 4-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-N-ACETYLMURAMYL-L-ALA-D-GLU AMIDE
• N-Acetyl-beta-D-Glucosaminyl-N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
• D-α-Glutamine, N-[N-acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]muramoyl]-L-alanyl-
• (4R)-4-((2S)-2-((2R)-2-(((3R,4R,5S,6R)-3-acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoic acid
• N-?Acetyl-?β-?D-?glucosaminyl-?N-?acetylmuramyl-?L-?alanyl-?D-?isoglutamine
• 70280-03-4
• C27H45N5O16
• Dipeptides and Tripeptides
• Dipeptides
• BioChemical
• Amino Acids and Peptides
• Biochemicals and Reagents