Bis(2,2,6,6-tetramethyl-4-piperidyl)sebacat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R23:Giftig beim Einatmen.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augensch?den.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Chemische Eigenschaften
White solid
Verwenden
T770 (Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate) can be used as a hindered amine UV stabilizer in plastic materials. It can be used in the manufacturing and packaging of pharmaceutical products. Titanium oxide(TiO
2)/T770 may be used in amine induced light stabilizers in the synthesis of recyclable water-based polyurethane with poly(oxytetramethylene)glycol (PTMG).
Allgemeine Beschreibung
Bis(2,2,6,6-tetramethyl-4-piperidyl) (T770) sebacate is a low molecular weight ultra violet (UV) hindered amine light stabilizer (HALS) made up of nitroxyl radicals. It acts as a heat controller that can react with phenolic antioxidants incorporated in polymers.
Biologische Aktivit?t
Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate(BTMPS; Tinuvin 770) is a sterically hindered amine light and radiation stabilizer produced by Ciba-Geigy, widely used in plastics, that inhibits nicotinic acetylcholine receptors expressed in Xenopus oocytes in a use-dependent manner. BTMPS is a symmetrical conjugate of methylated piperidines that are potent inhibitors on their own, but the kinetics of inhibition and recovery are faster than BTMPS. For neuronal nicotinic receptor subunit combinations, the time constant for recovery from inhibition by BTMPS is approximately 1 to 4 h. Muscle-type receptors (α 1-, β 1-γ, and δ subunits) are also inhibited by BTMPS, but control responses are fully restored after a 5 min washout. Hybrids of muscle and neuronal subunits containing neuronal β subunits (α 1-, β 2-, γ, and δ and α-1-, β 4-, and γ-δ) blocked in a more irreversible manner than normal muscle-type receptors, suggesting an interaction between BTMPS and neuronal acetylcholine receptor β subunits. Glutamate receptors were not inhibited by BTMPS. Exposure to agonist solutions from certain plastic syringes that release BTMPS also resulted in a use-dependent inhibition of nicotinic receptors.
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Bis(2,2,6,6-tetramethyl-4-piperidyl)sebacat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte