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AMN082 DIHYDROCHLORIDE

AMN082 DIHYDROCHLORIDE Struktur
83027-13-8
CAS-Nr.
83027-13-8
Englisch Name:
AMN082 DIHYDROCHLORIDE
Synonyma:
AMN 082;AMN082 free base;AMN 082 dihydrochlor;AMN082 DIHYDROCHLORIDE;AMN082 free base, 10 mM in DMSO;N1,N2-Dibenzhydrylethane-1,2-diamine;N,N'-bis(diphenylMethyl)ethylenediaMine;1,2-Ethanediamine, N1,N2-bis(diphenylmethyl)-;N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE;N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride
CBNumber:
CB6849458
Summenformel:
C28H28N2
Molgewicht:
392.54
MOL-Datei:
83027-13-8.mol

AMN082 DIHYDROCHLORIDE Eigenschaften

Schmelzpunkt:
105.5 °C
Siedepunkt:
533.7±45.0 °C(Predicted)
Dichte
1.086±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at +4°C
L?slichkeit
DMSO : 12.5 mg/mL (31.84 mM; ultrasonic and warming and heat to 60°C)
pka
8.38±0.29(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white

Sicherheit

AMN082 DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

The first selective mGlu 7 agonist. Potently inhibits cAMP accumulation and stimulates GTP γ S binding in recombinant cells and on membranes expressing mGlu 7 (EC 50 = 64-290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μ M. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.

AMN082 DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

AMN082 DIHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 57)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32281 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739
 info@dycnchem.com China 53900 58
J & K SCIENTIFIC LTD. 18210857532
 jkinfo@jkchemical.com China 96815 76
821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 12952 65
Bide Pharmatech Ltd. 400-164-7117 13681763483
 product02@bidepharm.com China 42446 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
 3008007409@qq.com China 71826 60
  • AMN 082
  • N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE
  • N,N'-BIS(DIPHENYLMETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE
  • AMN082 DIHYDROCHLORIDE
  • N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride
  • N,N'-bis(diphenylMethyl)ethylenediaMine
  • AMN 082 dihydrochlor
  • AMN082 free base
  • locomotor,allosteric,AMN082 free base,AMN 082,blood-brain,stress,hormone,Inhibitor,AMN-082,inhibit,sensitization,AMN-082 free base,oral,Metabotropic glutamate receptors,mGluR,barrier
  • 1,2-Ethanediamine, N1,N2-bis(diphenylmethyl)-
  • AMN082 free base, 10 mM in DMSO
  • N1,N2-Dibenzhydrylethane-1,2-diamine
  • 83027-13-8
  • C28H28N22ClH
  • C28H28N22HCl
  • Glutamate
  • Glutamate receptor
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