Endothelin-3 (human, rat) (trifluoroacetate salt) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ET_A and ET_B (K_bs = 1.05 and 1.49, respectively). It induces β-arrestin recruitment in CHO-K1 cells expressing human ET_A and ET_B (pD₂s = 7.31 and 9.44, respectively). Endothelin-3 increases blood pressure in spontaneously hypertensive and normotensive rats when administered at doses of 310 and 955 pmol/kg, respectively. It also stimulates migration and adhesion of enteric neural crest cells (ENCCs) to the embryonic gut in mice via interaction with ET_B. Mutations in the endothelin-3 gene, Edn3, induce distal aganglionosis caused by failed colonization of ENCCs in the hindgut and lack of ENCC migration to the ileo-caecal junction in mice.

Endothelin-3 (human, rat) (trifluoroacetate salt) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Endothelin-3 (human, rat) (trifluoroacetate salt) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	6838	58

---

• Endothelin-3 (human, rat) (trifluoroacetate salt)