Anti-Ubiquitously transcribed X chromosome tetratricopeptide repeat protein Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

ANTI-KDM6A antibody produced in rabbit has been used in western blotting and immunoprecipitation.

Allgemeine Beschreibung

Lysine-specific demethylase 6A (KDM6A) is a tumor suppressor gene mapped to human chromosome Xp11.3. The gene codes for histone H3 lysine 27 (H3K27) demethylase, which is a member of the switch/sucrose non-fermentable (SWI/SNF) family.

Biochem/physiol Actions

Lysine-specific demethylase 6A (KDM6A) counteracts zeste homolog 2 (EZH2) function and induces tumor suppression by stimulating gene transcription of E-cadherin, cell cycle regulators and tumor-suppressing subchromosomal transferable fragments. It also eliminates trimethylation marks from histone 3 lysine 27 (H3K27) and supports histone demethylase activity through its catalytic JmjC domain. Mutation in the gene leads to the development of a rare congenital anomaly syndrome, Kabuki syndrome (KS).

Anti-Ubiquitously transcribed X chromosome tetratricopeptide repeat protein Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Anti-Ubiquitously transcribed X chromosome tetratricopeptide repeat protein Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Merck Millipore	1-400-889-1988 400-889-1988	bioscience@merckgroup.com	China	6839	58
Merck KGaA	21-20338288	ordercn@merckgroup.com	China	6394	58
Beijing Biosynthesis Biotechnology Co Ltd	400-9019800	sales@bioss.com.cn	China	6102	58

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• ANTI-KDM6A antibody produced in rabbit
• Anti-Ubiquitously transcribed X chromosome tetratricopeptide repeat protein
• Anti-Ubiquitously transcribed TPR protein on the X chromosome
• Anti-UTX
• bA386N14.2
• KABUK2
• UTX
• lysine (K)-specific demethylase 6A
• KDM6A
• UTX human