EGFR Inhibitor III Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

EGFR Inhibitor III is which inhibits EGFR- kinase activity, blocking phosphorylation.

Allgemeine Beschreibung

A cell-permeable quinazolinyl-chloroacetamide compound that selectively and irreversibly blocks EGFR autophosphorylation with no effect on the expression levels of EGFR, and suppresses leiomyoma and myometrical cell proliferation (IC₅₀ = 0.7 μM and 1.1 μM, respectively). Shown to induce apoptosis and cell cycle arrest, and in combination with Genistein (Cat. No. 345834) completely suppress leiomyoma cell proliferation.

Biochem/physiol Actions

Target IC50: 0.7 μM and 1.1 μM suppressesing leiomyoma and myometrical cell proliferation, respectively

EGFR Inhibitor III Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

EGFR Inhibitor III Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Merck KGaA	21-20338288	ordercn@merckgroup.com	China	6394	58
Santa Cruz Biotechnology Inc	021-60936350	scbt@scbt.com	China	6594	58

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• EGFR Inhibitor III
• EGFR Inhibitor III - CAS 733009-42-2 - Calbiochem
• Acetamide, 2-chloro-N-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-quinazolinyl]-
• 733009-42-2
• C16H10Cl3FN4O