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CGP 35348

CGP 35348 Struktur
123690-79-9
CAS-Nr.
123690-79-9
Englisch Name:
CGP 35348
Synonyma:
C P 35348;CGP 35348;CGP 35348 hydrate;CGP 35348, GABAB antagonist;(3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID;Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-;P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid;Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-;(3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate;spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
CBNumber:
CB4386728
Summenformel:
C8H20NO4P
Molgewicht:
225.22
MOL-Datei:
123690-79-9.mol

CGP 35348 Eigenschaften

storage temp. 
−20°C
L?slichkeit
H2O: >10 mg/mL
Aggregatzustand
solid
Farbe
white
Wasserl?slichkeit
Soluble in water (100mM)

Sicherheit

WGK Germany  3

CGP 35348 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CGP 35348 hydrate has been used as a γ-aminobutyric acid-B (GABAB) receptor inhibitor:
  • to study its effects on intrinsic optical signal (IOS) in rat hippocampus
  • alone or in combination with sodium salicylate to study its effects on auditory responses in the rat′s dorsal cortex of rat
  • to study its effects on hepatocellular carcinoma cells (HCC)

Biologische Aktivit?t

Selective, brain penetrant GABA B receptor antagonist (IC 50 = 34 μ M as measured in rat cortical membranes). Has higher affinity for postsynaptic versus presynaptic receptors.

Biochem/physiol Actions

CGP 35348 is a γ-aminobutyric acid-B (GABAB) receptor antagonist. It has a higher affinity towards post-versus presynaptic receptors that can penetrate the blood-brain barrier.

CGP 35348 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

3-aminopropyl(diethoxymethyl)-phosphinic acid ethyl ester ethyl 2-cyanoethyl(diethoxymethyl)phosphinate Kohlenstoff

Downstream Produkte

CGP 35348 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 52)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32281 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903
 3008007409@qq.com China 71826 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
 klq@cw-bio.com China 6443 55
BOC Sciences --
 info@bocsci.com USA 0 65

123690-79-9()Verwandte Suche:

  • CGP 35348
  • (3-AMINOPROPYL)(DIETHOXYMETHYL)PHOSPHINIC ACID
  • (3-Aminopropyl)(diethoxymethyl)phosphinic acid hydrate
  • CGP 35348 hydrate
  • P-(3-Aminopropyl)-P-(diethoxymethyl)phosphinic acid
  • Phosphinic acid, (3-aminopropyl)(diethoxymethyl)-
  • spatial learning,neuromuscular,neonatal damage,CGP-35348,brain penetrant,GABA Receptor,CGP35348,Gamma-aminobutyric acid Receptor,centrally,GABAB,CGP 35348,Inhibitor,γ-Aminobutyric acid Receptor,inhibit,active
  • Phosphinic acid, P-(3-aminopropyl)-P-(diethoxymethyl)-
  • C P 35348
  • CGP 35348, GABAB antagonist
  • 123690-79-9
  • C8H20NO4P
  • GABA/Glycine receptor
  • GABA
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