Morpholin-3-on
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- CAS-Nr.
- 109-11-5
- Bezeichnung:
- Morpholin-3-on
- Englisch Name:
- morpholin-3-one
- Synonyma:
- 3-MORPHOLINONE;3-Oxomorpholine;in-3-on;3-morpholone;JACS-109-11-5;Morpholin-3-on;MORPHOLIN-3-ONE;morpholine-3-one;3-Ketomorpholine;3-Morpholinone>
- CBNumber:
- CB2121662
- Summenformel:
- C4H7NO2
- Molgewicht:
- 101.1
- MOL-Datei:
- 109-11-5.mol
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Morpholin-3-on Eigenschaften
- Schmelzpunkt:
- 103.0 to 107.0 °C
- Siedepunkt:
- 142°C/7mmHg(lit.)
- Dichte
- 1.122±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- L?slichkeit
- soluble in Methanol
- Aggregatzustand
- powder to crystal
- pka
- 14.37±0.20(Predicted)
- Farbe
- White to Almost white
- InChI
- InChI=1S/C4H7NO2/c6-4-3-7-2-1-5-4/h1-3H2,(H,5,6)
- InChIKey
- VSEAAEQOQBMPQF-UHFFFAOYSA-N
- SMILES
- N1CCOCC1=O
- CAS Datenbank
- 109-11-5(CAS DataBase Reference)
- EPA chemische Informationen
- 3-Morpholinone (109-11-5)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| S-S?tze: |
24/25 |
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| HS Code |
29349990 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H318 |
Verursacht schwere Augensch?den. |
Schwere Augensch?digung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
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Morpholin-3-on Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.
Einzelnachweise
He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889.
Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980.
Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015).
Morpholin-3-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Morpholin-3-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 292)Lieferanten
109-11-5(Morpholin-3-on)Verwandte Suche:
- Morpholin-3-on
- MORPHOLIN-3-ONE
- morpholine-3-one
- 3-morpholone
- 3-Ketomorpholine
- Morpholin-3-one ,98%
- in-3-on
- JACS-109-11-5
- 3-Morpholinone>
- morpholin-3-one USP/EP/BP
- 3-morpholone/ 3-Ketomorpholine
- 3-KetomorpholineQ: What is
3-Ketomorpholine Q: What is the CAS Number of
3-Ketomorpholine Q: What is the storage condition of
3-Ketomorpholine
- 3-MORPHOLINONE
- 3-Oxomorpholine
- 3-Morpholinone (6CI, 7CI, 8CI, 9CI, ACI)
- 3-Morpholin-4-ylne
- 3-Ketomorpholine 98%
- 109-11-5
- Heterocycles
- Heterocycles series
