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(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid

PERUVOSIDE Struktur
1182-87-2
CAS-Nr.
1182-87-2
Bezeichnung:
(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid
Englisch Name:
PERUVOSIDE
Synonyma:
Enordin;encordin;Pervoside;peruvosid;PERUVOSIDE;(22)-enolide;PERUVOSIDE(RG);Peruvoside (90%);PERUVOSIDE USP/EP/BP;cannogeninthevetoside
CBNumber:
CB0266619
Summenformel:
C30H44O9
Molgewicht:
548.66
MOL-Datei:
1182-87-2.mol

(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Eigenschaften

Schmelzpunkt:
161-164°C
alpha 
D22 -71.7° (c = 1.54 in methanol)
Siedepunkt:
540.83°C (rough estimate)
Dichte
1.1277 (rough estimate)
Brechungsindex
1.5500 (estimate)
storage temp. 
2-8°C
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
12.92±0.70(Predicted)
Aggregatzustand
powder
Farbe
light yellow

Sicherheit

Kennzeichnung gef?hrlicher T
R-S?tze: 23/24/25
S-S?tze: 36/37/39-45
WGK Germany  3
RTECS-Nr. FH4915000
Toxizit?t cat,LD50,intravenous,145ug/kg (0.145mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)CARDIAC: CHANGE IN RATE,Archives Internationales de Pharmacodynamie et de Therapie. Vol. 126, Pg. 412, 1960.

(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Verwenden

Peruvoside is a cardiac glycoside with the same inotropic and chronotropic effects on heart function as Ouabain (O714500).

Enzyminhibitor

This cardiotonic glycoside or cardenoide (FW = 548.67 g/mol; CAS 1182- 87-2), named systematically as (3b,5b)-3-(6-deoxy-3-O-methyl-a-Lglucopyranosyl)oxyl-14-hydroxy-19-oxocard-20(22)-enolide, a component of neriperside from Thevetia neriifolia (yellow oleander) resembles oubain in its inotropic (force of contraction) and chronotropic (rate of contraction) effects on heart function. Orally administered peruvoside is effective in treating congestive heart failure. Note the structural similarities of the aglycon to digitoxigenin. Target(s): Na+ /K+ -exchanging ATPase.

(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 62)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 3751 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22866 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38665 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8615965530500
nickzhang@hangyubiotech.com China 10968 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Mensura Group Limited
+8618109034517
1058503172@qq.com China 2900 58
J & K SCIENTIFIC LTD. 18210857532
jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109
market03@meryer.com China 40228 62
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50

1182-87-2((3β,5β)-3-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolid)Verwandte Suche:


  • PERUVOSIDE
  • (22)-enolide
  • (3β,5β)-3-(6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxyl)-14-hydroxy-19-oxocard-20(22)-enolide
  • 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-5β,14β-card-20(22)-enolide
  • Cannogenin α-L-thevetoside
  • Enordin
  • Pervoside
  • (3β,5β)-3-[(6-Deoxy-3-O-Methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
  • Peruvoside (90%)
  • (3beta,5beta)-3-[(6-deoxy-3-O-methyl-alpha-L\-glucopyranosyl)oxy]-14-hydroxy-19-oxocard-20(22)-enolide
  • PERUVOSIDE FROM THEVETIA NERIIFOLIA
  • PERUVOSIDE(RG)
  • (3-beta,5-beta)-oxy-19-oxo
  • 3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxy-19-oxo-card-20
  • cannogeninalpha-l-thevetoside
  • cannogeninthevetoside
  • card-20(22)-enolide,3-((6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydr
  • encordin
  • peruvosid
  • CANNOGENNIN-ALPHA-L-THEVETOSIDE
  • [3BETA,5BETA]-3-[6-DEOXY-3-O-METHYL-ALPHA-L-GLUCOPYRANOSYL)OXYL]-14-HYDROXY-19-OXOCARD-20[22]-ENOLIDE
  • PERUVOSIDE USP/EP/BP
  • (3S,5R,8R,9S,10R,13R,14S,17R)-3-[(2R,3S,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-14-hydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-10-carbaldehyde
  • Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-19-oxo-, (3β,5β)-
  • 1182-87-2
  • C30H44O9
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