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Tegaserod

Tegaserod Struktur
145158-71-0
CAS-Nr.
145158-71-0
Englisch Name:
Tegaserod
Synonyma:
TEGASEROD;Tegaserode;Tegaserod USP/EP/BP;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;(E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
CBNumber:
CB0225423
Summenformel:
C16H23N5O
Molgewicht:
301.39
MOL-Datei:
145158-71-0.mol

Tegaserod Eigenschaften

Schmelzpunkt:
155°
Siedepunkt:
470.6±48.0 °C(Predicted)
Dichte
1.18
storage temp. 
2-8°C
Aggregatzustand
Solid
pka
15.81±0.30(Predicted)
Farbe
White to off-white
CAS Datenbank
145158-71-0(CAS DataBase Reference)

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 20/21/22-36/37/38
S-S?tze: 36/37-36-26

Tegaserod Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Verwenden

Treatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).

Indications

Tegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.

Clinical Use

Tegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.

Tegaserod Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tegaserod Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 81)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29856 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49732 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040
1087@dideu.com China 3292 58
TargetMol Chemicals Inc.
+17819995354
marketing@targetmol.com United States 32281 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10244 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15227 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 987 58
changzhou huayang technology co., ltd
+8615250961469
2571773637@qq.com China 9647 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763
sales@tnjchem.com China 25356 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58

145158-71-0()Verwandte Suche:


  • TEGASEROD
  • 2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide
  • Tegaserode
  • Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
  • Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10
  • Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3
  • Tegaserod USP/EP/BP
  • Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-
  • (E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide
  • 145158-71-0
  • C16H23N5O
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