伊曲茶堿雜質(zhì)
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- CAS號(hào):
- 160434-48-0
- 英文名:
- 4-DesMethyl Istradefylline
- 英文別名:
- Itraphylline impurities6;4-Desmethyl Istradefylline;Istradefylline Impurity 14;Itraphylline impurities869;Istradefylline M1 metabolite;4-DesMethyl Istradefylline impurity;Istradefylline 4-O-Desmethyl Impurity;(E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione;1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- 中文名:
- 伊曲茶堿雜質(zhì)
- 中文別名:
- 4-去甲基異氟烷;伊曲茶堿雜質(zhì)14;伊曲茶堿雜質(zhì)869;4-去甲基伊曲茶堿
- CBNumber:
- CB12695351
- 分子式:
- C19H22N4O4
- 分子量:
- 370.4
- MOL File:
- 160434-48-0.mol
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伊曲茶堿雜質(zhì)化學(xué)性質(zhì)
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沸點(diǎn):
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604.8±65.0 °C(Predicted)
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密度:
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1.30±0.1 g/cm3(Predicted)
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酸度系數(shù)(pKa):
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9.88±0.31(Predicted)
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伊曲茶堿雜質(zhì)性質(zhì)、用途與生產(chǎn)工藝
4-Desmethyl Istradefylline 是 Istradefylline 的代謝物。Istradefylline 是一種有效的，選擇性的，可口服的 adenosine A2A receptor 拮抗劑，在帕金森疾病模型試驗(yàn)中，Ki 值為 2.2 nM。
用途
4-Desmethyl Istradefylline is an impurity of Istradefylline (I927000), a selective A(2A) antagonist used in the treatment of Parkinson鈥檚 disease. 4-Desmethyl Istradefylline have also been shown to exh
ibit inhibitory potency towards adenosine A2A receptors and is classified as its an adenosine A2A receptor antagonist.
伊曲茶堿雜質(zhì)
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
160434-48-0, 伊曲茶堿雜質(zhì) 相關(guān)搜索:
- Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
- 雜質(zhì)對(duì)照品
- 伊曲茶堿雜質(zhì)869
- 4-去甲基異氟烷
- 4-去甲基伊曲茶堿
- 伊曲茶堿雜質(zhì)14
- 160434-48-0
- 4-Desmethyl Istradefylline
- Itraphylline impurities6
- Itraphylline impurities869
- Istradefylline M1 metabolite
- Istradefylline 4-O-Desmethyl Impurity
- 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-7-methyl-, (E)- (9CI)
- Istradefylline Impurity 14
- 4-DesMethyl Istradefylline impurity
- (E)-1,3-diethyl-8-(4-hydroxy-3-methoxystyryl)-7-methyl-1H-purine-2,6(3H,7H)-dione