65094-22-6
65094-22-6 結(jié)構(gòu)式
基本信息
二氟甲基膦酸二乙酯
溴二氟甲基 二乙基膦酸酯
BROMODIFLUOROMETHYL DIETHYLPHOSPHONATE
Diethyl bromodifluoromethanephosphonate
DIETHYL (BROMODIFLUOROMETHYL)PHOSPHONATE
Bromodifluoromethyl diethyl phosphonate~Diethyl bromodifluoromethanephosphonate
BromodifluoromethylphosphonicAcidDiethylEsterDiethylBromodifluoromethylphosphonate
Bromodifluoromethyl diethylphosphonate 97%
Bromodifluoromethyldiethylphosphonate97%
1-[[Bromo(difluoro)methyl]-ethoxyphosphoryl]oxyethane
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
制備方法
75-61-6
122-52-1
65094-22-6
在氮?dú)獗Ｗo(hù)下，將二溴二氟甲烷（209.8 g，1 mol）緩慢滴加至裝有磁力攪拌器的亞磷酸三乙酯（153.5 g，0.925 mol）的無(wú)水乙醚（450 mL）溶液中。滴加完畢后，將反應(yīng)體系緩慢升溫至室溫，隨后加熱回流20小時(shí)。反應(yīng)完成后，通過(guò)減壓蒸餾除去揮發(fā)性溶劑，收集沸點(diǎn)為50-52℃（1 mmHg）的餾分，得到無(wú)色液體產(chǎn)物二乙基（溴二氟甲基）膦酸酯（256.3 g，產(chǎn)率96%）。產(chǎn)物結(jié)構(gòu)經(jīng)1H NMR（CDCl3）確認(rèn)：δ 4.35（m，4H），1.35（m，6H）；13C NMR（CDCl3）確認(rèn)：δ 122.9, 119.8, 118.6, 115.4, 114.2, 111.1, 66.59, 66.50, 16.56, 16.48。
參考文獻(xiàn)：
[1] Journal of Organometallic Chemistry, 1997, vol. 529, # 1-2, p. 267 - 278
[2] Phosphorus, Sulfur and Silicon and Related Elements, 1997, vol. 122, p. 247 - 259
[3] Patent: US2004/225146, 2004, A1. Location in patent: Page 4
[4] Journal of Fluorine Chemistry, 2011, vol. 132, # 10, p. 815 - 828
[5] Patent: WO2006/78698, 2006, A1. Location in patent: Page/Page column 64-65
常見問(wèn)題列表
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | L16715 | 溴二氟甲基膦酸二乙酯, 97% Diethyl (bromodifluoromethyl)phosphonate, 97% | 65094-22-6 | 1g | 216元 |
| 2025/05/22 | L16715 | 溴二氟甲基膦酸二乙酯, 97% Diethyl (bromodifluoromethyl)phosphonate, 97% | 65094-22-6 | 5g | 325元 |
| 2025/05/22 | L16715 | 溴二氟甲基膦酸二乙酯, 97% Diethyl (bromodifluoromethyl)phosphonate, 97% | 65094-22-6 | 25g | 2495元 |