2731-73-9
中文名稱(chēng)
3-氯-L-丙氨酸
英文名稱(chēng)
3-Chloro-L-alanine
CAS
2731-73-9
分子式
C3H6ClNO2
分子量
123.54
MOL 文件
2731-73-9.mol
更新日期
2025/03/17 09:52:05
2731-73-9 結(jié)構(gòu)式
基本信息
中文別名
(S)-3-氯丙氨酸3-氯-L-丙氨酸
L-3-氯丙氨酸
英文別名
3-CHLORO-L-ALANINEBETA-CHLORO-ALANINE
BETA-CHLORO-L-ALANINE
H-ALA(3-CL)-OH
H-ALA(BETA-CL)-OH
H-BETA-CHLORO-ALA-OH
L-ALA-3-CL
S-3-Cl-Alanine
B-Chloro-L-Alanine
H-B-Chloro-Ala-OH
(2R)-2-Amino-3-chloropropionic acid
(R)-2-Amino-3-chloropropanoic acid
[R,(-)]-2-Amino-3-chloropropionic acid
3-Chloro-L-alanine,97%
所屬類(lèi)別
生物化工：丙氨酸類(lèi)衍生物物理化學(xué)性質(zhì)
熔點(diǎn)156 °C
沸點(diǎn)243.6±30.0 °C(Predicted)
密度1.2776 (rough estimate)
折射率1.5000 (estimate)
儲(chǔ)存條件Store at 0°C
溶解度DMSO（少許）、水（少許）
酸度系數(shù)(pKa)1.89±0.10(Predicted)
形態(tài)固體
顏色白色至灰白色
水溶解性可溶
水溶解性可溶于水
CAS 數(shù)據(jù)庫(kù)2731-73-9
常見(jiàn)問(wèn)題列表
生物活性
β-Chloro-L-alanine是抑制多種酶的抑菌氨基酸類(lèi)似物，抑制包括蘇氨酸脫氨酶和丙氨酸消旋酶。靶點(diǎn)
Bacterial
體外研究
β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B.