1435-55-8
中文名稱
氫化奎尼定
英文名稱
HYDROQUINIDINE
CAS
1435-55-8
EINECS 編號(hào)
215-862-5
分子式
C20H26N2O2
MDL 編號(hào)
MFCD00135599
分子量
326.43
MOL 文件
1435-55-8.mol
更新日期
2025/02/18 16:45:33
1435-55-8 結(jié)構(gòu)式
基本信息
中文別名
氫化奎尼定二氫奎尼啶
雙氫奎尼丁
二氫奎寧定
氫奎寧啶
(5-乙基-1-氮雜雙環(huán)[2.2.2]辛烷-7-基)-(6-甲氧基喹啉-4-基)甲醇
二氫奎尼丁
氫化奎寧定
英文別名
DIHYDROQUINIDINEHYDROQUINIDINE
(9s)-10,11-dihydro-6’-methoxycinchonan-9-ol
(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol
10,11-Dihydroquinidine
11-dihydro-6’-methoxy-1(9s)-cinchonan-9-o
6'-Methoxy-10,11-dihydrocinchonan-9-ol
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
Hydroconchinine
Hydroconquinine
hydroquinidine anhydrous
Hydroxyquinidine
2-Hydroquinidine
Hydroquinidine (base and/or unspecified salts)
(1β,4β,7R,αS)-α-(6-Methoxy-4-quinolyl)-5β-ethyl-1-azabicyclo[2.2.2]octane-7-methanol
Hydroqninidine
(5-Ethyl-1-azabicyclo[2.2.2]octan-7-yl)-(6-methoxyquinolin-4-yl)methanol
(8a,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol
所屬類別
原料藥：抗心律失常藥物理化學(xué)性質(zhì)
熔點(diǎn)169-170 °C(lit.)
比旋光度226 º (C=2 IN ETOH)
沸點(diǎn)464.47°C (rough estimate)
密度1.1117 (rough estimate)
折射率1.6800 (estimate)
儲(chǔ)存條件Keep in dark place,Sealed in dry,Room Temperature
溶解度chloroform: 0.1 g/mL, clear
酸度系數(shù)(pKa)12.80±0.20(Predicted)
形態(tài)結(jié)晶固體
顏色White to off-white
旋光性 (optical activity)[α]25/D +226°, c = 2 in ethanol
Merck13,4831
BRN91441
InChIKeyLJOQGZACKSYWCH-LHFMAAMQSA-N
CAS 數(shù)據(jù)庫(kù)1435-55-8(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息Hydroquinidine(1435-55-8)
常見(jiàn)問(wèn)題列表
應(yīng)用
氫化奎尼定可作為有機(jī)合成中間體和醫(yī)藥中間體，主要用于實(shí)驗(yàn)室研發(fā)過(guò)程和化工醫(yī)藥生產(chǎn)過(guò)程中。生物活性
Hydroquinidine (Dihydroquinidine, Hydroconchinine, Hydroconquinine, Dihydroquinine) 是抗心律失常藥。