120-46-7
120-46-7 結(jié)構(gòu)式
基本信息
1,3-二苯基丙二酮
ω-苯甲酰基苯乙酮
二苯甲酰甲烷
二苯甲醯甲烷
二苯甲?；淄? 98+%
1,3-diphenylpropane-1,3-dione
DBM
DIBENZOYLMETHANE
,3-Diphenyl-propane-1,3-dione
1,3-Diphenyl-1,3-propanediamine
1,3-diphenyl-3-propanedione
1,3-Diphenylpropanedione
2-Benzoylacetophenone
3-Propanedione,1,3-diphenyl-1
arenzu dk 2
-Benzoylacetophenone
-Benzoylace-tophenone
Dibenzoylmethan
hodiastab 83
-Hydroxy-chalkone
karenzudk2
omega-Benzoylacetophenone
Phenyl phenacyl ketone
Phenyl-hydroxystyrylketone
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
應(yīng)用領(lǐng)域
知名試劑公司產(chǎn)品信息
Dibenzoylmethane, 98%(120-46-7)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2025/02/08 | HY-W009731 | 二苯甲酰基甲烷 Dibenzoylmethane | 120-46-7 | 500mg | 500元 |
| 2025/02/08 | HY-W009731 | 二苯甲?；淄?BR>Dibenzoylmethane | 120-46-7 | 10mM * 1mLin DMSO | 550元 |
| 2025/02/08 | HY-W009731 | 二苯甲酰基甲烷 Dibenzoylmethane | 120-46-7 | 1 g | 700元 |
常見問題列表
二苯甲酰甲烷是甘草中的次要成分，可激活 Nrf2 并預(yù)防各種癌癥和氧化損傷。Dibenzoylmethane 是姜黃素的類似物，會引起 Keap1 解離和 Nrf2 的核易位。
Dibenzoylmethane (10, 20, 30, 40, 50 μM; 6 hours) treatment concentration-dependently increases the mRNA level of HO-1 but has no effect on the mRNA level of Nrf2 in HepG2 cells. Dibenzoylmethane induces HO-1 and Nrf2 protein expression, and the induction diminishes after 12 h.
Dibenzoylmethane (10, 20, 30, 40, 50 μM; 2 hours) concentration-dependently increases the phosphorylated protein levels of Erk1/2, p38MAPK, JNK, AMPK, and Akt in HepG2 cells.
Dibenzoylmethane does not show significant cytotoxicity.
Dibenzoylmethane (200, 500 mg/kg/day; ip; for three consecutive days) pretreatment significantly reduces both the area and the severity of necrosis, as well as the leukocyte infiltration, at a dose of 200 mg/kg in wild-type and Nrf2 knockout mice.
Dibenzoylmethane protectes against CCl4-induced (1:49,v/v, 10 ml/kg) liver damage in wild-type mice.