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ChemicalBook--->CAS DataBase List--->912656-34-9

912656-34-9

912656-34-9 Structure

912656-34-9 Structure
IdentificationBack Directory
[Name]

XEN907
[CAS]

912656-34-9
[Synonyms]

XEN907
XEN907; XEN 907; XEN-907
1'-pentylspiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one
Spiro[furo[2,3-f]-1,3-benzodioxole-7(6H),3'-[3H]indol]-2'(1'H)-one, 1'-pentyl-
1-CYCLOPENTYL-1,2-DIHYDRO-6',10',12'-TRIOXASPIRO[INDOLE-3,4'-TRICYCLO[7.3.0.0^{3,7}]DODECANE]-1',3'(7'),8'-TRIEN-2-ONE
[Molecular Formula]

C21H21NO4
[MDL Number]

MFCD25371548
[MOL File]

912656-34-9.mol
[Molecular Weight]

351.4
Chemical PropertiesBack Directory
[Melting point ]

88-90 °C
[Boiling point ]

566.9±50.0 °C(Predicted)
[density ]

1.34±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

-0.19±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

XEN907 is a novel spirooxindole NaV1.7 blocker with IC50 of 3 nM. It shows a further 10-fold increase in potency, which represents a promising structure for further optimization efforts in vitro.
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