| Identification | More | [Name]
2,5-Dimethylnitrobenzene | [CAS]
89-58-7 | [Synonyms]
2,5-DIMETHYLNITROBENZENE
2-NITRO-1,4-DIMETHYLBENZENE
2-NITRO-4-XYLENE
2-NITRO-P-XYLENE
NITRO-P-XYLENE
1,4-dimethyl-2-nitro-benzen
1-Nitro-2,5-dimethylbenzene
2,5-Dimethyl-1-nitrobenzene
2-Nitro-para-xylene
2-nitro-p-xylen
p-Xylene, 2-nitro-
p-Nitroxylene.
2-NITRO-P-XYLENE/2,5-DIMETHYLNITROBENZENE
1,4-Dimethyl-2-nitrobenzene
Benzene, 1,4-dimethyl-2-nitro
1,4-Dimethyl-6-nitrobenzene
2,5-Dimethy-nitrobenzene | [EINECS(EC#)]
201-920-7 | [Molecular Formula]
C8H9NO2 | [MDL Number]
MFCD00024284 | [Molecular Weight]
151.16 | [MOL File]
89-58-7.mol |
| Safety Data | Back Directory | [Risk Statements ]
R36/37:Irritating to eyes and respiratory system .
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
1665 | [RTECS ]
ZE4686600 | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29042090 | [Toxicity]
LD50 orl-rat: 2440 mg/kg 85JCAE -,420,86 |
| Hazard Information | Back Directory | [General Description]
Clear pale yellow to amber liquid. | [Reactivity Profile]
1,4-DIMETHYL-2-NITROBENZENE(89-58-7) is incompatible with strong oxidizers and strong bases . | [Air & Water Reactions]
Insoluble in water. | [Fire Hazard]
This compound is probably combustible. | [Chemical Properties]
pale yellow liquid | [Synthesis Reference(s)]
Synthesis, p. 690, 1978 DOI: 10.1055/s-1978-24859 | [Safety Profile]
Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx. | [Synthesis]
GENERAL STEPS: All reactions were carried out in a 50 mL two-necked round-bottomed flask equipped with a water condenser and a magnetic stirrer. In a typical experiment, a mixture of zeolite HBEA-25 (Si/Al = 25, 0.11 g), o-xylene (0.60 mL, 5 mmol), 65% nitric acid (0.68 mL, 10 mmol) with acetic anhydride (5.0 mL) was stirred and reacted for 10 h at room temperature. After completion of the reaction, the zeolite was removed by filtration and the filtrate was washed sequentially with NaHCO3 solution (3 x 10 mL) and distilled water (3 x 10 mL). The organic phase was separated, dried with anhydrous sodium sulfate and filtered to give a straw yellow liquid product. The isomer distribution and yield of the product were estimated by gas chromatography internal standard method based on peak area. The crude product was further purified by column chromatography and structural identification was carried out by comparing the analytical data with real samples. | [References]
[1] Russian Journal of Organic Chemistry, 1993, vol. 29, # 3.2, p. 457 - 466
[2] Zhurnal Organicheskoi Khimii, 1993, vol. 29, # 3, p. 546 - 558
[3] Tetrahedron Letters, 1996, vol. 37, # 4, p. 513 - 516
[4] Journal of Fluorine Chemistry, 2008, vol. 129, # 6, p. 524 - 528
[5] Organic Letters, 2018, vol. 20, # 11, p. 3197 - 3201 |
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