| Identification | More | [Name]
Ethylenebis(oxyethylenenitrilo)tetraacetic acid | [CAS]
67-42-5 | [Synonyms]
1,2-BIS[2-[BIS(CARBOXYMETHYL)AMINO]ETHOXY]ETHANE
1,2-DI(2-AMINOETHOXY)ETHANE-NNN'N'-TETRA-ACETIC ACID
2,2'-ETHYLENEDIOXYBIS[ETHYLIMINODI(ACETIC ACID)]
3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID
BIS(AMINOETHYL)GLYCOLETHER-N,N,N,N'-TETRAACETIC ACID
CHEL-DE
CHEL-DE(R)
CHEL(R)-DE
EGTA
EGTAZIC ACID
ETHYLENE-BIS(OXYETHYLENENITRILLO)TETRAACETIC ACID
ETHYLENEBIS(OXYETHYLENENITRILO)TETRAACETIC ACID
ETHYLENEDIOXYBIS(ETHYLAMINE)-N,N,N',N'-TETRAACETIC ACID
ETHYLENEDIOXYBIS(ETHYLENENITRILO)-TETRAACETIC ACID
ETHYLENE GLYCOL-BIS(2-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC ACID
ETHYLENE GLYCOL BIS[2-AMINOETHYL ETHER]TETRAACETIC ACID
ETHYLENE GLYCOL-BIS(2-AMINOETHYL)-N,N,N',N'-TETRAACETIC ACID
ETHYLENEGLYCOL-BIS-(AMINOETHYLETHER)-TETRAACETIC ACID
ETHYLENE GLYCOL BIS(B-AMINOETHYL ETHER)-N,N'-TETRACETIC ACID
ETHYLENE GLYCOL-BIS-(BETA-AMINO-ETHYL ETHER)-N,N,N',N-TETRAACETIC ACID | [EINECS(EC#)]
200-651-2 | [Molecular Formula]
C14H24N2O10 | [MDL Number]
MFCD00004291 | [Molecular Weight]
380.35 | [MOL File]
67-42-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White to slightly off-white powder | [Melting point ]
241 °C (dec.)(lit.)
| [Boiling point ]
507.99°C (rough estimate) | [bulk density]
450kg/m3 | [density ]
1.2838 (rough estimate) | [refractive index ]
1.4590 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
| [form ]
Crystalline Powder | [pka]
1.47±0.10(Predicted) | [color ]
White | [biological source]
synthetic (organic) | [Water Solubility ]
slightly soluble | [Merck ]
14,3529 | [BRN ]
1717370 | [CAS DataBase Reference]
67-42-5(CAS DataBase Reference) | [EPA Substance Registry System]
67-42-5(EPA Substance) | [Absorption]
cut-off at 263nm in 1 M NaOH at 0.1M |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
2
| [RTECS ]
AH3760000
| [TSCA ]
Yes | [HS Code ]
29225000 | [Safety Profile]
Poison by
intraperitoneal route. Moderately toxic by
ingestion. When heated to decomposition it
emits toxic fumes of NOx. See also
GLYCOL ETHERS. | [Toxicity]
LD50 orally in Rabbit: 3587 mg/kg |
| Questions And Answer | Back Directory | [Description]
Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium.
|
| Hazard Information | Back Directory | [Chemical Properties]
White to slightly off-white powder | [Uses]
Pharmaceutic aid. EGTA. | [Definition]
ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively. | [reaction suitability]
reagent type: chelator | [Biological Activity]
Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells. | [storage]
Room temperature | [Purification Methods]
Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.] |
| Well-known Reagent Company Product Information | Back Directory | [Acros Organics]
Ethylenebis(oxyethylenenitrilo)tetraacetic acid, 97%(67-42-5) | [Alfa Aesar]
Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 97%(67-42-5) | [Sigma Aldrich]
67-42-5(sigmaaldrich) | [TCI AMERICA]
Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid,>95.0%(T)(67-42-5) |
|
|