| Identification | More | [Name]
Cetylpyridinium chloride monohydrate | [CAS]
6004-24-6 | [Synonyms]
1-CETYLPYRIDINIUM CHLORIDE MONOHYDRATE
1-HEXADECYLPYRIDINIUM CHLORIDE MONOHYDRATE
1-N-HEXADECYLPYRIDINIUM CHLORIDE MONOHYDRATE
CETYLPYRIDINII CHLORIDUM
CETYLPYRIDINIUM CHLORIDE
CETYLPYRIDINIUM CHLORIDE H2O
CETYLPYRIDINIUM CHLORIDE MONOHYDRATE
CPC
CPC MONOHYDRATE
HEXADECYLPYRIDINIUM CHLORIDE MONOHYDRATE
N-CETYLPYRIDINIUM CHLORIDE MONOHYDRATE
N-HEXADECYLPYRIDINIUM CHLORIDE MONOHYDRATE
Cetylpyridiniumchloride,monoh
Pyridinium,1-hexadecyl-,chloride,monohydrate
cetyl pyridium chloride
Cetylpyridinum chloride
CETYLPYRIDINIUM CHLORIDE SIGMAULTRA
HEXADECYLPYRIDINIUM CHLORIDE MONO-HYDR&
CETYLPYRIDINIUM CHLORIDE CRYSTALLINE
HEXADECYLPYRIDINIUM CHLORIDE MONOHYDRATE, PH EUR | [EINECS(EC#)]
204-593-9 | [Molecular Formula]
C21H40ClNO | [MDL Number]
MFCD00149977 | [Molecular Weight]
358 | [MOL File]
6004-24-6.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light beige powder | [Melting point ]
81-84 °C
| [bulk density]
370kg/m3 | [storage temp. ]
Store at RT. | [solubility ]
H2O: soluble0.5M, clear, colorless to faintly yellow | [form ]
Powder | [color ]
White | [PH]
5.0-5.4 (10g/l, H2O, 20℃) | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides. | [Water Solubility ]
Soluble in water, alcohol, chloroform | [Merck ]
14,2032 | [BRN ]
3578606 | [InChI]
InChI=1S/C21H38N.ClH.H2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H;1H2/q+1;;/p-1 | [InChIKey]
NFCRBQADEGXVDL-UHFFFAOYSA-M | [SMILES]
C1=[N+](CCCCCCCCCCCCCCCC)C=CC=C1.[Cl-].[H]O[H] | [LogP]
1.699 (est) | [CAS DataBase Reference]
6004-24-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T+,N,Xi | [Risk Statements ]
R25:Toxic if swallowed.
R26:Very Toxic by inhalation.
R38:Irritating to the skin.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S7/9:Keep container tightly closed and in a well-ventilated place .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
UN 2811 6.1/PG 1
| [WGK Germany ]
3
| [RTECS ]
UU5075000
| [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
I | [HS Code ]
29333999 | [Toxicity]
LD50 in rats (mg/kg): 250 s.c.; 6 i.p.; 30 i.v.; 200 orally (Nelson, Lyster) |
| Hazard Information | Back Directory | [Chemical Properties]
white to light beige powder | [Uses]
antiinfective (topical) | [Uses]
Pharmaceutic aid (preservative). | [Definition]
ChEBI: Cetylpyridinium chloride monohydrate is a hydrate. It contains a cetylpyridinium chloride. | [General Description]
Cetylpyridinum chloride is a quaternary ammonium compound and an active ingredient of antiseptic oral mouth rinses with broad spectrum antimicrobial activity. Its mode of action involves a rapid bactericidal effect on Gram-positive pathogens and a fungicide effect on certain yeasts.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. | [Purification Methods]
Crystallise the chloride from MeOH or EtOH/diethyl ether and dry it in vacuo. [Moss et al. J Am Chem Soc 108 788 1986, Lennox & McClelland J Am Chem Soc 108 3771 1986, Beilstein 20 V 233.] | [Toxics Screening Level]
The initial threshold screening level (ITSL) for cetylpyridinium chloride monohydrate is 1.8 μg/m3 based on an annual averaging time. |
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