| Identification | More | [Name]
3-TRIMETHYLSILYL-2-PROPYN-1-OL | [CAS]
5272-36-6 | [Synonyms]
1-TRIMETHYLSILYLPROPARGYL ALCOHOL
3-TRIMETHYLSILANYL-PROP-2-YN-1-OL
3-TRIMETHYLSILYL-2-PROPYN-1-OL
3-TRIMETHYLSILYL-2-PROPYNE-1-OL
3-(TRIMETHYLSILYL)PROPARGYL ALCOHOL
TIMTEC-BB SBB009061
TRIMETHYLSILYLPROPARGYL ALCOHOL
2-Propyn-1-ol, 3-(trimethylsilyl)-
3-(trimethylsilyl)-2-propyn-1-o
3-Trimethylsilylpropargylalcohol3-Trimethylsilyl-2-propyn-1-ol
3-(Trimethylsilyl)propargyl alcohol, 98+% | [EINECS(EC#)]
226-094-5 | [Molecular Formula]
C6H12OSi | [MDL Number]
MFCD00002913 | [Molecular Weight]
128.24 | [MOL File]
5272-36-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow liquid | [Melting point ]
63.5-65.0 °C | [Boiling point ]
76 °C11 mm Hg(lit.)
| [density ]
0.865 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.451(lit.)
| [Fp ]
152 °F
| [storage temp. ]
2-8°C
| [solubility ]
Benzene (Sparingly) | [form ]
Liquid | [pka]
13.71±0.10(Predicted) | [color ]
Clear yellow | [Specific Gravity]
0.865 | [Water Solubility ]
Not miscible with water. | [Hydrolytic Sensitivity]
4: no reaction with water under neutral conditions | [Sensitive ]
Moisture Sensitive | [BRN ]
1902505 | [InChIKey]
ZVGCJDPEKKEYES-UHFFFAOYSA-N | [CAS DataBase Reference]
5272-36-6(CAS DataBase Reference) | [NIST Chemistry Reference]
3-Trimethylsilylpropargyl alcohol(5272-36-6) | [EPA Substance Registry System]
5272-36-6(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
2810 | [WGK Germany ]
3
| [F ]
8-10 | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29319090 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow liquid | [Uses]
Trimethylsilylpropargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma. |
|
|